2018年

Keystone Symposia Heart Failure: Crossing the Translational Divide. January 14-18, 2018, Keystone, USA

1. Morita Y, Muta E, Tanada Y, Shioi T, Kimura T, Kato T. Spatiotemporal and integrative analysis of the transcriptome and metabolome response to systemic energetic starvation with cardiac dysfunction (Oral presentation).

EHRA 2018 March 18-20, 2018, Barcelona, Spain

1. T Yoshizawa, S Shizuta, A Komasa, Y Sasaki, A Kobori, T Kimura (Kyoto and Kobe, JP). The second generation cryoballoon ablation is safe and useful for paroxysmal atrial fibrillation in super-elderly patients over 80 years: a report from two high-volume centers.

TCTATP 2018 April 28-May 1, 2018, Seoul,Korea

1. Junichi Tazaki,Takeshi Kimura. Coil Embolization for Type II Endoleak after EVAR Candidates and Outcomes.

86th EAS CONGRESS May 5-8, 2018, Lisbon, Portugal

1. Takeshi Kimura. High-intensity pitavastatin therapy further improves clinical outcomes in Japanese patients with stable coronary artery disease.

Regulatory & Non-Coding RNAs at Cold Spring Harbor Laboratory May 15-19, 2018, New York , USA.

1. Tetsushi Nakao, Takahiro Horie, Tomohiro Nishino, Hitoo Nishi, Fumiko Nakazeki, Yuya Ide, Satoshi Koyama, Masahiro Kimura, Kazuhisa Sakamoto, Kenji Minatoya, Satoko Ohno, Hiroki Aoki, Takeshi Kimura, Koh Ono. MicroRNA-33 deteriorates vascular inflammation and abdominal aortic aneurysm via distinct several mechanisms.

Asian Pacific Society of Cardiology (APSC) Congress May 17-20, 2018, Taipei, Taiwan

1. Takeshi Kimura. Optimal Lipid Lowering Therapy in Japanese Patients: REAL-CAD and Beyond.
2. Takahiro Horie, Tomohiro Nishino, Tetsushi Nakao, Fumiko Nakazeki, Yuya Ide, Satoshi Koyama, Masahiro Kimura, Koji Hasegawa、Takeshi Kimura, Koh Ono. SREBF1/MicroRNA- 33b axis exhibits potent effect on unstable atherosclerotic plaque formation in vivo.
3. Masahiro Kimura, Satoshi Koyama, Yukihito Sato, Koh Ono, Takeshi Kimura. Dynamic changes of serum microRNA-122-5p through therapeutic courses indicates amelioration of acute liver injury accompanied by acute cardiac decompensation.

Technion-Kyoto Joint meeting, May 21, 2018, Kyoto, Japan

1. Yoshinori Yoshida. Induction of cardiomyocyte maturation for biomedical applications.

23rd Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy May 26-27, 2018, Kyoto, Japan

1. Koh Ono. SREBF1/MicroRNA-33b axis exhibits potent effect on unstable atherosclerotic plaque formation in vivo.
2. Noboru Ashida. Role of inflammatory signaling in vascular calcification.
3. Takeru Makiyama. Modelling long-QT syndrome with human iPS cells and development of new pharmacotherapies.
4. Hirohiko Kohjitani, Shigeya Koda, Yukiko Himeno, Takeru Makiyama, Yimin Wuriyanghai, Yuta Yamamoto, Takeshi Kimura, Akinori Noma, Akira Amano. Cell-specific Mathematical Modeling of hiPSC-CMs and Its Potential for Prediction of Drug Testing.
5. Yimin Wuriyanghai, Takeru Makiyama, Suguru Nishiuchi, Yuta Yamamoto, Sayako Hirose, Mamoru Hayano, Takeshi Harita, Hirohiko Kohjitani, Fumika Yokoi, Jingshan Gao, Chonabayashi Kazuhisa, Yoshinori Yoshida, Seiko Ohno, Minoru Horie, Takeshi Kimura.　Development of Homozygous Lamin A/C Deficient Human Induced Pluripotent Stem Cell Model for Analyzing the Pathophysiological Mechanism of Lamin A/C-related Cardiomyopathy.

Heart Failure 2018 May 26-29, 2018, Vienna, Austria

1. Y Yoshikawa, Y Tamaki, H Yaku, E Yamamoto, N Ozasa, Y Inuzuka, T Morimoto, Y Nakagawa, T Kato, T Kimura. Prescription rate of beta-blockers and factors of its use or nonuse in patients hospitalized for acute heart failure (from the KCHF Registry).
2. Hidenori Yaku, T Kato, Y Yoshikawa, Y Inuzuka, Y Tamaki, T Kimura. Functional decline during hospitalization and outcomes of patients with acute heart failure.
3. K Hotta, R Taniguchi, Y Sato, E Yamamoto, H Yaku, N Ozasa, T Kato, T Morimoto, T Kimura. Clinical characteristics of atrial fibrillation in patients with acute heart failure; insights from The Kyoto Congestive Heart Failure (KCHF) registry.
4. Y Tamaki, H Yaku, E Yamamoto, N Ozasa, Y Inuzuka, T Morimoto, Y Nakagawa, T Kato, T Kimura2. Effects of beta blocker use prior to admission in patients with acute decompensated heart failure.

XVIIIth International Symposium on Atherosclerosis June 10-11, 2018, Toronto, Canada

1. Koh Ono. SREBF1/MicroRNA-33b axis exhibits potent effect on unstable atherosclerotic plaque formation in vivo.

ISSCR 16th Annual Meeting June 20-23, 2018, Melbourne, Australia

1. Manabu Kasamoto, Takeshi Hatani, Shunsuke Funakoshi, Chikako Okubo, Tadashi Takaki, Kenji Miki, Takeshi Kimura, Yoshinori Yoshida. The Discovery of Brand-new Compound which Accelerate the Cell Cycle to Achieve the Efficient iPS cell-derived Cardiomyocyte Engraftment to the Infarction Modeled Mouse.
2. Julia Junghof, Koichi Nakayama, Yoshinori Yoshida. Toward in vitro construction of iPSCderived human heart-like tissue.
3. Kenji Miki, Kohei Deguchi, Shigeru Kondo, Tsukasa Sugo, Sachiko Imaichi, Teruyoshi Yamashita, Mie Yoshimatsu, Takako Sono, Yuki Naka, Stephanie Napier, Fumi Yoshinaka, Norihisa Tamura, Tomoyuki Nishimoto, Yoshinori Yoshida. ERR GAMMA AGONIST AND SKP2 INHIBITOR ARE NOVEL MATURATION FACTORS IN HUMAN IPSC-DERIVED CARDIOMYOCYTES.
4. Kazuhisa Chonabayasi, Akira Watanabe, Akifumi Takaori-Kondo, Yoshinori Yoshida. iPS technology revealed the genetic and functional diversity present in amyelodysplastic syndrome patient.

CSI 2018 June 27-28, 2018, Frankfurt, Germany

1. Masao Imai. Succesful transcatheter closure of residual atrial septal defect after surgical closure~ First report for sinus venosus type with eustachian valve.

The 2018 International Congress on Electrocardiology (ICE 2018) Organized by the International Society of Electrocardiology (ISE) and the International Society for Holter and Noninvasive Electrocardiology (ISHNE) June 28-30, 2018, Chiba, Japan

1. Takeru Makiyama. Human induced pluripotent stem cell models for inherited arrhythmias.

12th Catholic International Stem Cell Symposium June 29, 2018, Seoul, South Korea

1. Yoshinori Yoshida. Generation of mature cardiomyocytes from human pluripotent stem cells.

18th World Congress of Basic and Clinical Pharmacology July 1-6, 2018, Kyoto, Japan

1. Ohno M, Chen P-M, Hiwasa T, Nishi K, Saijo S, Sakamoto J, Morita Y, Watanabe S, Kuwabara Y, Ono K, Imai M, Inoue K, Murai T, Kita T, Kimura T, and Nishi E. Nardilysin is a Promising Biomarker for the Early Diagnosis of Acute Coronary Syndrome.
2. Iwasaki H, Morino K, Ohno M, Sakurai H, Maegawa H, Nishi E, Imamura T. MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis by targeting transcriptional coactivator p300 in human induced pluripotent stem cells.

The 43rd FEBS Congress July 6-13, 2018, Prague, Czech Republic

1. Yoshinori Hiraoka, Hikari Yoshitane, Mikiko Ohno, Yusuke Morita, Rina Nunokawa, Kiyoto Nishi, Noriaki Kume, Takeshi Kimura, Yoshitaka Fukada and Eiichiro Nishi. Nardilysin, a new PER2-interacting protein, regulates the mammalian circadian clock.

ESC Congress 2018 August 25-29, Munich, Germany

1. Takeshi Kimura. Optimal antithrombotic treatment beyond the first year post PCI for ACS.
2. Takeshi Kimura. Stent type and duration of dual antiplatelet therapy.
3. Kato T, Uemura Y, Naya M, Momose M, Matsumoto N, Suzuki E, Hida S, Nakajima T, Yamauchi T, Tamaki N. Impact of renal dysfunction on choice of diagnostic imaging, treatment strategy, and outcomes in patients with stable angina: A report from J-COMPASS study.
4. Hirohiko Kohjitani, Shigeya Kouda, Yukiko Himeno, Takeru Makiyama, Fumika Yokoi, Sayako Hirose, Yimin Wuriyanghai, Yuta Yamamoto, Minoru Horie, Takeshi Kimura, Akinori Noma, Akira Amano. Significance of cell-specific precise computer simulation using new mathematical models of human induced pluripotent stem cell derived cardiomyocyte in drug testing.
5. Yugo Yamashita, T Morimoto, T Toyota, H Shiomi, T Makiyama, K Ono, T Kimura.Asian patients versus non-Asian patients in the efficacy and safety of direct oral anticoagulants relative to vitamin K antagonist for venous thromboembolism: a systemic review and meta-analysis.
6. Y Yoshikawa, M Nakamoto, T Hoshi, M Nakamura, S Imai, Y Kawase, H Matsuo, N Saito. A novel software for on-site estimation of fractional flow reserve using coronary computed tomography images.
7. Y Yoshikawa, Y Yamashita, T Morimoto, H Amano, T Takase, S Hiramori, Kitae Kim, M Oi, M Toyofuku, Y Tsuyuki, J Sakamoto, H Shiomi, T Makiyama, K Ono, T Kimura. Sex Differences in the Clinical Characteristics and Outcomes of Patients with Venous Thromboembolism: from the COMMAND VTE Registry.
8. Daisuke Yoshinaga, Shiro Baba, Hirofumi Shibata, Takuya Hirata, Takeru Makiyama, Ryuta Nishikomori. Can patient-derived iPSCs be applied to phenotypic cell-based high throughput screening assessment to distinguish between different types of long-QT syndrome?

China-Japan International Conference on Atherosclerosis 2018 August 30-31, 2018, Xian, China

1. Koh Ono. ‘Functions of microRNA-33a/b on inflammation and atherosclerosis’ .

40th European Society of Clinical Nutrition Congress September 1-4, 2018, Madrid, Spain

1. Takezawa A, Tamamura Y, Shimizu T, Nishikimi T. REHABILITATION PERIOD AND SWALLOWING FUNCTION RATHER THAN HEMATOMA VOLUME ARE RELATED TO IMPROVEMENT OF ADL IN PATIENTS WITH MILD TOMODERATE CEREBRAL HEMORRHAGE.
2. Shimizu T, Tamamura Y, Takezawa A, Namikawa T, Banba K, Nishikimi T. LOWER ACTIVITY OF DAILY LIVING DECREASES SERUM ALBUMIN AND SALIVARY SECRETION WHICH MAY CAUSE ASPIRATION PNEUMONIA IN THE ELDERLY.
3. Shimizu T, Tamamura Y, Takezawa A, Nishikimi T. AMELIORATION OF SWALLOWING DISORDER MAY IMPROVE THE NUTRITION AND REHABILITATION IN THE PATIENTS WITH CEREBRAL HEMORRHAGE.
4. Tamamura Y, Shimizu T, Takezawa A, Nishikimi T. RECOVERY FROM GAIT DISTURBANCE IN CEREBRAL HEMORRHAGE BY REHABILITATION IS ASSOCIATED WITH NUTRITION.

TERMIS2018 September 7, 2018, Kyoto, Japan

1. Yoshinori Yoshida. Modeling of cardiac diseases using iPS cells.

Forum of Regenerative Medicine in Taipei September 20, 2018, Taipei, Taiwan

1. Yoshinori Yoshida. Cardiac regeneration using human iPSC derived cardiomyocytes.

ISH(Internal Society of Hypertension) 2018 Scientific Meeting September 20-23, 2018, Baijing, China

1. Toshio Nikishikimi, Yasuaki Nakagawa, Hideyuki Kinoshita, Hideaki Inazumi, Kenji Moriutchi, Hiromu Yanagisawa, Koichiro Kuwahara, Hiroyuki Takahama, Naoto Minamino, Takeshi Kimura. Pro-B type natriuretic peptide (BNP) to total BNP ratio is involved in the pathphysiology of acute and chronic heart failure: elucidateon of molecura mechanism.

The 11th Asia Pacific Heart Rhythm Society Scientific Session October 17-20, 2018, Taipei, Taiwan

1. Yoshinori Yoshida. Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes.
2. Yoshinori Yoshida. Disease Modeling of Cardiac Diseases Using Induced Pluripotent Stem Cells.
3. T Yoshizawa, S Shizuta, T Aizawa, S Yamagami, A Komasa, T Kimura. The Second Generation Cryoballoon Ablation Is Safe and Useful for Atrial Fibrillation in Super-Elderly Patients over 80 Years.
4. A Komasa, S Shizuta, M Tanaka, T Aizawa, S Yamagami, T Yoshizawa, T Kimura. Impact of the Timing for Recurrence after Cryoballoon Ablation for Paroxysmal Atrial Fibrillation.
5. Asami Kashiwa, Takeru Makiyama, Seiko Ohno, Yimin Wuriyanghai, Yuta Yamamoto, Sayako Hirose, Hirohiko Kohjitani, Jing Shan Gao, Minoru Horie, Takeshi Kimura, Overlapping Brugada Syndrome Associated with SCN5A Mutations in Patients with Sick Sinus Syndrome Treated with Permanent Pacemakers.
6. Yuta Yamamoto, Takeru Makiyama, Yimin Wuriyanghai, Hirohiko Kohjitani, Sayako Hirose, Jingshan Gao, Asami Kashiwa, Taisuke Ishikawa, Seiko Ohno, Kazuhisa Chonabayashi, 5Kenji Suda, Yoshinori Yoshida, Minoru Horie, Naomasa Makita, Takeshi Kimura. Single Cell Electrophysiological Analysis of iPS Cell-derived Cardiomyocytes generated from Long-QT syndrome patients carrying a CALM2 mutation using membrane voltage imaging system.
7. Yimin Wuriyanghai, Takeru Makiyama, Yuta Yamamoto, Suguru, Nishiuchi, Sayako Hirose, Hirohiko Kohjitani, Jingshan Gao, Asami Kashiwa, Seiko Ohno, Minoru Horie, Takeshi Kimura. Analysis of Disease-Causing Mechanism of Lamin A/C-Related Cardiomyopathy Using Homozygous Lamin A/C Knock out Human Induced Pluripotent Stem Cell Model.
8. Jingshan Gao, Takeru Makiyama, Seiko Ohno, Yuta Yamamoto, Yimin Wuriyanghai, Hirohiko Kohjitani, Asami Kashiwa, Sayako Hirose, Minoru Horie, Takeshi Kimura. Three-dimensional Structural Analysis of Mutant Ryanodine Receptor Type 2 Channels Associated with Catecolaminergic Polymorphic Ventricular Tachycardia.

TCT2018 October 21-25, 2018, San Diego, US

1. Watanabe Hirotoshi. Association of Age With the Risk of Thrombotic and Bleeding Event After PercutaneousCoronary Intervention.
2. Yukiko Nakano, Satoshi Shizuta, Akihiro Komasa, Takeshi Morimoto, Hisaki Masuda, Hiroki Shiomi, Kentaro Nakai, Satoru Suwa, Takeshi Aoyama, Mamoru Takahashi, Yuko Onishi, Toshiaki Mano, Mitsuo Matsuda, Makoto Motooka, Hirofumi Tomita, Moriaki Inoko, Takatoshi Wakeyama, Nobuhisa Hagiwara, Masaharu Akao, Kenji Ando, Yutaka Furukawa, Yoshihisa Nakagawa, Kazushige Kadota, Kazuya Kawai, and Takeshi Kimura: On behalf of the OACALONE Study Investigators. Oral Anticoagulation With vs Without Single Antiplatelet Therapy in Patients With Atrial Fibrillation Beyond One Year After Coronary Stent Implantation.
3. Yasuaki Takeji. The Impact of Diabetes Mellitus on the Long-term Risk for Heart Failure in Patients who Underwent Coronary Revascularization.

the 2nd Joint Australia-Japan/Japan-Australia joint RNA meeting 2018 November 5-7, 2018, 2018, Sapporo, Japan

1. Takahiro Horie. SREBF1/MicroRNA-33b axis exhibits potent effect on unstable atherosclerotic plaque formation in vivo.
2. Masahiro Kimura, Satoshi Koyama, Yukihito Sato, Koh Ono, Takeshi Kimura. Dynamic changes of serum microRNA-122-5p through therapeutic courses indicates amelioration of acute liver injury accompanied by acute cardiac decompensation.
3. Shuhei Tsuji, Yasuhide Kuwabara, Takahiro Horie, Yasuhiro Nakashima, Naoya Sowa, Yuya Ide, Masahiro Kimura, Randolph Ruiz Rodoriguez, Tomohiro Yamasaki, Chiharu Ohtani, Toshimitsu Watanabe, Sijia Xu, Takeshi Kimura, and Koh Ono. A Novel Long Intergenic Noncoding RNA, Lionheart, Protects the Heart from Pressure Overload.

American Heart Association Scientific Sessions 2018 November 10-12, 2018, Chicago, USA

1. Yugo Yamashita, Takeshi Morimoto, Hidewo Amano, Toru Takase, Seiichi Hiramori, Kitae Kim, Maki Oi, Tomohisa Tada, Koichiro Murata, Yoshiaki Tsuyuki, Jiro Sakamoto, Hiroki Shiomi, Takeru Makiyama, Koh Ono, Takeshi Kimura. The validation of simplified PESI score for identification of low-risk patients with pulmonary embolism: From the COMMAND VTE Registry.
2. Yugo Yamashita, Takeshi Morimoto, Hidewo Amano, Toru Takase, Seiichi Hiramori, Kitae Kim, Maki Oi, Tomohisa Tada, Koichiro Murata, Yoshiaki Tsuyuki, Jiro Sakamoto, Hiroki Shiomi, Takeru Makiyama, Koh Ono, Takeshi Kimura. Influence of Baseline Thrombocytopenia on Clinical Outcomes in Patients with Venous Thromboembolism: From the COMMAND VTE Registry.
3. Takeshi Hatani, Kazuhisa Chonabayashi, Yoshihiko Fujita, Takeshi Kimura, Hirohide Saito, Yoshinori Yoshida. Efficient Purification of Human iPSC-derived Cardiomyocytes in a Large Scale Using a Synthetic MicroRNA Switch and Magnetic-activated Cell Sorting.
4. Takeshi Hatani, Shunsuke Funakoshi, Thomas J. Deerinck, Eric A. Bushong, Takeshi Kimura, Mark H. Ellisman, Masahiko Hoshijima, Yoshinori Yoshida. Nano-structural Analysis of Engrafted Human iPSC-derived Cardiomyocytes in a Mouse Model of Myocardial Infarction Using APEX2.
5. Manabu Kasamoto, Shunsuke Funakoshi, Takeshi Hatani, Takeshi Kimura, Yoshinori Yoshida. EFFICIENT CARDIAC REGENERATION THERAPY BY CELL CYCLE ACTIVATION OF IPSC-DERIVED CARDIOMYOCYTES.
6. Wiviott S, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker T, Bhatt D, Leiter L, McGuire D, Wilding J, Gausse-Nilsson IAM, Langklide AM, Johansson PA, Sabatine S. The Dapagliflozin Effect on Cardiovascular Events (DECLARE)- TIMI 58. American Heart Association Scientific Meeting, Late Breaking Session.

Meet the Expert 2018 November 10, 2018, Chicago, USA

1. Takeshi Hatani. Cardiac Regeneration Therapy.

VERVE Symposium 2018 December 6-8, 2018, Sydney, Austraria

1. Junichi Tazaki,Takeshi Kimura. Management of type II endoleak before and after EVAR for AAA.

Copyright(C) by Department of the circulatory organs,
Kyoto University Hospital. All Rights Reserved.