1. Tanaka M, Yamamoto H, Kita T, Yokode M: Early prediction of the need for non-routine discharge planning for the elderly. Arch Gerontol Geriatr, 47: 1-7, 2008.
  2. Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, Horiguchi M, Okuda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H: Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets. J Biol Chem, 283(13): 8746-55, 2008.
  3. Aramaki Y, Mitsuoka H, Toyohara M, Jinnai T, Kanatani K, Nakajima K, Mukai E, Yamada Y, Kita T, Inagaki N, Kume N: Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells. Atherosclerosis, 198: 272-9, 2008.
  4. Mima A, Arai H, Matsubara T, Abe H, Nagai K, Tamura Y, Torikoshi K, Araki M, Kanamori H, Takahashi T, Tominaga T, Matsuura M, Iehara N, Fukatsu A, Kita T, Doi T: Urinary Smad1 is a novel marker to predict later onset of mesangial matrix expansion in diabetic nephropathy. Diabetes, 57: 1712-22, 2008.
  5. Xu Y, Arai H, Murayama T, Kita T, Yokode M: Vascular remodeling and mobilization of bone marrow-derived cells in cuff-induced vascular injury in LDL receptor knockout mice. Chin Med J (Engl), 121(3): 220-6, 2008.
  6. Ozasa N, Morimoto T, Furukawa Y, Shizuta S, Nishiyama K, Kita T, Kimura T : Effects of ICD implantation on quality-adjusted life years in patients with congestive heart failure. Int J Cardiol, 123: 213-6, 2008.
  7. Wu YW, Tadamura E, Kanao S, Yamamuro M, Okayama S, Ozasa N, Toma M, Kimura T, Kita T, Marui A, Komeda M, Togashi K: Left ventricular functional analysis using 64-slice multidetector row computed tomography: comparison with left ventriculography and cardiovascular magnetic resonance. Cardiology, 109: 135-42, 2008.
  8. Kawato M, Shirakawa R, Kondo H, Higashi T, Ikeda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H: Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway. J Biol Chem, 283(1): 166-74, 2008.
  9. Komori H, Arai H, Kashima T, Huby T, Kita T, Ueda Y: Coexpression of CLA-1 and human PDZK1 in murine liver modulates HDL cholesterol metabolism. Arterioscler Thromb Vasc Biol, 28: 1298-303, 2008.
  10. Tanaka K, Ishikawa Y, Yokoyama M, Origasa H, Matsuzaki M, Saito Y, Matsuzawa Y, Sasaki J, Oikawa S, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; JELIS Investigators, Japan. : Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial. Stroke, 39(7): 2052-8, 2008.
  11. Brinkley TE, Kume N, Mitsuoka H, Brown MD, Phares DA, Ferrell RE, Kita T, Hagberg JM: Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels. Exp Physiol, 93(9): 1085-90, 2008.
  12. Ozasa N, Furukawa Y, Morimoto T, Tadamura E, Kita T, Kimura T: Relation among left ventricular mass, insulin resistance, and hemodynamic parameters in type 2 diabetes. Hypertens Res, 31(3): 425-432, 2008.
  13. Itakura H, Kita T, Mabuchi H, Matsuzaki M, Matsuzawa Y, Nakaya N, Oikawa S, Saito Y, Sasaki J, Shimamoto K; J-LIT Study Group: Relationship between coronary events and serum cholesterol during 10 years of low-dose simvastatin therapy: long-term efficacy and safety in Japanese patients with hypercholesterolemia in the Japan Lipid Intervention Trial (J-LIT) Extension 10 Study, a prospective large-scale observational cohort study. Circ J, 72: 1218-24, 2008.
  14. Saito Y, Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K; JELIS Investigators, Japan: Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS). Atherosclerosis, 200:135-40, 2008.
  15. Kimura T, Morimoto T, Furukawa Y, Nakagawa Y, Shizuta S, Ehara N, Taniguchi R, Doi T, Nishiyama K, Ozasa N, Saito N, Hoshino K, Mitsuoka H, Abe M, Toma M, Tamura T, Haruna Y, Imai Y, Teramukai S, Fukushima M, Kita T: Long-term outcomes of coronary-artery bypass graft surgery versus percutaneous coronary intervention for multivessel coronary artery disease in the bare-metal stent era. Circulation, 118: S199-209, 2008.
  16. Higuchi H, Hara M, Yamamoto K, Miyamoto T, Kinoshita M, Yamada T, Uchiyama K, Matsumori A: Mast cell play a critical role in the pathogenesis of viral myocarditis. Circulation 118; 363-372, 2008.
  17. Miura K, Matsumori A, Nasermoaddeli A, Soyama Y, Morikawa Y, Sakurai M, Kitabatake A, Nagai M, Inaba Y, Nakagawa H. Prognosis and prognostic factors in patients with idiopathic dilated cardiomyopathy in Japan: results from a nationwide study. Circ J. 72(3): 343-8, 2008.
  18. Shichi D, Matsumori A, Naruse T, Inoko H, Kimura A. HLA-DP? chain may confer the susceptibility to hepatitis C virus-associated hypertrophic cardiomyopathy. Int J Immunogegnet. 35(1): 37-43, 2008.
  19. Imai M, Kimura T, Toma M, Saito N, Nakanoue T, Tadamura E, Kita T, Inoue K.Inoue Stent-Graft Implantation for Thoracoabdominal Aortic Aneurysm Involving the Visceral Arteries. Eur J Vasc Endovasc Surg. 2008 Apr; 35(4): 462-5.
  20. Furukawa Y, Taniguchi R, Ehara N, Ozasa N, Haruna Y, Saito N, Doi T, Hoshino K, Shizuta S, Morimoto T, Imai Y, Teramukai S, Fukushima M, Kita T, Kimura T. Better survival with statin administration after revascularization therapy in Japanese patients with coronary artery disease. Circ J. 2008 Dec; 72(12): 1937-45. Epub 2008 Oct 24.
  21. Nakagawa Y, Nobuyoshi M, Yamaguchi T, Meguro T, Yokoi H, Kimura T, Hosoda S, Kanmatsuse K, Matsumori A, Sasayama S. Efficacy of Abciximab for Patients Undergoing Balloon Angioplasty. Circ J. 2009; 73:145-151. Epub ahead of print .2008 Nov.21.
  22. Kuge Y, Kume N, Ishino S, Takai N, Ogawa Y, Mukai T, Minami M, Shiomi M, Saji H: Prominent lectin-like oxidized LDL receptor-1 (LOX-1) expression in atherosclerotic lesions is associated with tissue factor expression and apoptosis in hypercholesterolemic rabbits. Biol. Pharm. Bull. 31: 1475-1482, 2008
  23. Ishino S, Mukai T, Kuge Y, Kume N, Ogawa M, Takai N, Kamihashi J, Shiomi M, Minami M, Kita T, Saji H: Targeting of lectinlike oxidized low-density lipoprotein receptor 1 (LOX-1) with 99mTc-labeled anti-LOX-1 antibody: Potential target for imaging of vulnerable plaque. J. Nuc. Med. 49: 1677-1685, 2008
  24. Brinkley TE, Kume N, Mitsuoka H, Phares DA, Hagberg JM: Elevated soluble lectin-like oxidized LDL receptor-1 (sLOX-1) levels in obese postmenopausal women. Obesity 16: 1454-1456, 2008
  25. Koshiyama H, Taniguchi A, Tanaka K, Kagimoto S, Fujioka Y, Hirata K, Nakamura Y, Iwakura A, Hara K, Yamamoto T, Kuroe A, Ohya M, Fujimoto S, Hamamoto Y, Honjo S, Ikeda H, Nabe K, Tsuda K, Inagaki N, Seino Y, Kume N: Effects of pitavastatin on lipid profiles and high-sensitivity CRP in Japanese subjects with hypercholesterolemia: Kansai Investigation of Statin for Hyperlipidemic Intervention in Metabolism and Endocrinology (KISHIMEN) Investigators. J. Atheroscler. Thromb. 15: 345-350, 2008
  26. Yamamoto H, Takahashi K, Watanabe H, Yoshikawa Y, Shirakawa R, Higashi T, Kawato M, Ikeda T, Tabuchi A, Morimoto T, Kita T, Horiuchi H: Evaluation of the antiplatelet effects of cilostazol, a phosphodiesterase 3 inhibitor, by VASP phosphorylation and platelet aggregation. Circ. J 72, 1844-1851, 2008
  27. Huang Y, Marui A, Sakaguchi H, Esaki J, Arai Y, Hirose K, S. Chandra Bir, Horiuchi H, Maruyama T, Ikeda T, Tabata Y, Komeda M: Sustained release of prostaglandin E1 potentiates the impaired therapeutic angiogenesis by basic fibroblast growth factor in diabetic murine hindlimb ischemia. Circ. J 72, 1693-1699, 2008
  28. Tabuchi A, Taniguchi R, Takahashi K, Kondo H, Kawato M, Morimoto T, Kimura T, Kita T, Horiuchi H: Aspirin action on whole blood-aggregation evaluated by the screen filtration pressure method. Circ J 72, 420-426, 2008.
  29. Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, Horiguchi M, Okuda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H: Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets. J Biol Chem. 283, 8746-8755, 2008.
  30. Kawato M, Shirakawa R, Kondo H, Higashi T, Ikeda T, Fukai S, Nureki O, Kita T, Horiuchi H: GTP-induced dense-granule secretion in platelets is mediated by Ral GTPase-exocyst pathway. J Biol Chem 283, 166-174, 2008.
  31. Ogata T, Ueyama T, Isodono K, Tagawa M, Takehara N, Kawashima T, Harada K, Takahashi T, Shioi T, Matsubara H, Oh H. MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol. 2008; 28: 3424-36.
  32. Ha T, Hua F, Liu X, Ma J, McMullen JR, Shioi T, Izumo S, Kelley J, Gao X, Browder W, Williams DL, Kao RL, Li C. Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovasc Res. 2008; 78: 546-53.
  33. Okabe T, Hattori M, Yuan Z, Kishimoto C: L-arginine ameliorates experimental autoimmune myocarditis by maintaining extracellular matrix and reducing cytotoxic activity of lymphocytes. Int. J. Exp. Path. 89: 382-388.
  34. Kishimoto C, Okabe T, Hattori M, Yuan Z: Naloxone, an opiate receptor antagonist, ameliorates acute experimental autoimmune myocarditis by reducing cytotoxic activities. J. Cardiovasc. Pharmacol. 52: 445-451.
  35. Kishimoto C, Ohmae M, Tomioka N: QRS voltages are transiently increased at the superacute stage of experimental myocarditis. Exp. Clin. Cardiol. 13: 15-18.
  36. Makiyama T, Akao M, Shizuta S, Doi T, Nishiyama K, Oka Y, Ohno S, Nishio Y, Tsuji K, Itoh H, Kimura T, Kita T, Horie M. A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation. J Am Coll Cardiol. 52:1327-34, 2008.
  37. Makiyama T, Akao M, Haruna Y, Tsuji K, Doi T, Ohno S, Nishio Y, Kita T, Horie M. Mutation analysis of the glycerol-3 phosphate dehydrogenase-1 like (GPD1L) gene in Japanese patients with Brugada syndrome. Circ J. 72:1705-6, 2008.
  38. Ohno S, Toyoda F, Zankov D, Yoshida H, Makiyama T, Tsuji K, Honda T, Obayashi K, Ueyama H, Shimizu W, Miyamoto Y, Kamakura S, Matsuura H, Kita T, Horie M. Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome. Hum Mutat. 30(4): 557-563, 2009.
  39. Ohno S, Kubota T, Yoshida H, Tsuji K, Makiyama T, Yamada S, Kuga K, Yamaguchi I, Kita T, Horie M. A novel mutation associated with Jervell and Lange-Nielsen syndrome in a Japanese family. Circ J. 72:687-93, 2008.
  40. Horie T, Ono K, Kinoshita M, Nishi H, Nagao K, Kawamura T, Abe Y, Wada H, Shimatsu A, Kita T, Hasegawa K: TG-interacting factor is required for the differentiation of preadipocytes. J Lipid Res. 2008; 49:1224-34.
  41. Horie T, Ono K, Nagao K, Nishi H, Kinoshita M, Kawamura T, Wada H, Shimatsu A, Kita T, Hasegawa K: Oxidative stress induces GLUT4 translocation by activation of PI3-K/Akt and dual AMPK kinase in cardiac myocytes. J Cell Physiol. 2008; 215:733-42.
  42. Matsumae H, Yoshida Y, Ono K, Togi K, Inoue K, Furukawa Y, Nakashima Y, Kojima Y, Nobuyoshi M, Kita T, Tanaka M: Inhibition of CCN1 suppressed neointimal hyperplasia in a rat balloon injury model. Arterioscler Thromb Vasc Biol. 2008; 28:1077-83.
  43. Satoh N, Wada H, Ono K, Yamakage H, Yamada K, Nakano T, Hattori M, Shimatsu A, Kuzuya H, Hasegawa K. Small dense LDL-cholesterol relative to LDL-cholesterol is a strong independent determinant of hypoadiponectinemia in metabolic syndrome. Circ J 2008; 72:932-9.
  44. Wada H, Abe M, Ono K, Morimoto T, Kawamura T, Takaya T, Satoh N, Fujita M, Kita T, Shimatsu A, Hasegawa K. Statins activate GATA-6 and induce differentiated vascular smooth muscle cells. Biochem Biophys Res Commun. 2008; 374:731-6.
  45. Maruyama R, Goto K, Takemura G, Ono K, Nagao K, Horie T, Tsujimoto A, Kanamori H, Miyata S, Ushikoshi H, Nagashima K, Minatoguchi S, Fujiwara T, Fujiwara H. Morphological and biochemical characterization of basal and starvation-induced autophagy in isolated adult rat cardiomyocytes. Am J Physiol Heart Circ Physiol. 2008; 295:H1599-607.
  46. Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K: Identification of p300-targeted acetylated residues in GATA-4 during hypertrophic responses in cardiac myocytes. J Biol Chem. 2008; 283:9828-35.
  47. Sugimoto M, Arai H, Tamura Y, Murayama T, Khaengkhan P, Nishio T, Ono K, Ariyasu H, Akamizu T, Ueda Y, Kita T, Harada S, Kamei K, Yokode M: Mulberry leaf ameliorates the expression profile of adipocytokines by inhibiting oxidative stress in white adipose tissue in db/db mice. Atherosclerosis. 2008 Oct 30. [Epub ahead of print]
  48. Tamura Y, Sugimoto M, Murayama T, Ueda Y, Kanamori H, Ono K, Ariyasu H, Akamizu T, Kita T, Yokode M, Arai H: Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db Mice. Arterioscler Thromb Vasc Biol. 2008; 28:2195-201.
  49. Matsuda M, Kobayashi Y, Masuda S, Adachi M, Watanabe T, Yamashita JK, Nishi E, Tsukita S, Furuse M: Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning. Exp Cell Res. 2008; 314: 939-49
  50. Hiraoka Y, Yoshida K, Ohno M, Matsuoka T, Kita T, Nishi E: Ectodomain shedding of TNF-alpha is enhanced by nardilysin via activation of ADAM proteases. Biochem. Biophs. Res. Commun. 2008; 370: 154-8
  51. Tanaka M, Endo S, Okuda T, Economides AN, Valenzuela DM, Murphy AJ, Robertson EJ, Sakurai T, Fukatsu A, Yancopoulos GD, Kita T, Yanagita M: Balance between BMP-7 and Uterine sensitization-associated gene-1 (USAG-1), a novel BMP antagonist in kidney disease and development. Kidney Int. 2008 Jan; 73(2): 181-91.
  52. Murashima-Suginami A, Takahashi K, Sakata T, Tsukamoto H, Sugai M, Yanagita M, Shimizu A, Sakurai T, Slavkin HC, Bessho K. Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse. Biochem Biophys Res Commun. 2008 May 16; 369(4): 1012-6.
  53. Yanagita M: Uterine Sensitization Associated Gene-1 (USAG-1): A Bone Morphogenetic Protein Antagonist in the Kidney. (book chapter) "TRANSFORMING GROWTH FACTOR-β IN CANCER THERAPY", edited by Sonia B. Jakowlew, PhD, Humana Press, 2008.
  54. Wada H, Hasegawa K, Terashima S, Satoh N, Inoue M, Iida Y, Yamakage H, Kitaoka S, Morimoto T, Fujita M, Shimatsu A, Takahashi Y. Knowledge and interest regarding smoking-related health risks in smokers and non-smokers. Self-rating depression scale score is a strong independent predictor of smoking cessation outcomes Smoking Control Science 2008; 4: 4-8.
  55. Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K. Identification of p300-targeted acetylated residues in GATA-4 during hypertrophic responses in cardiac myocytes. J Biol Chem. 2008; 283:9828-35.
  56. Matsumoto T, Fujita M, Tarutani Y, Yamane T, Takashima H, Nakae I, Horie M: Whole-body periodic acceleration enhances brachial endothelial function. Circ J 72(1): 139-143, 2008.
  57. Bir SC, Fujita M, Marui A, Hirose K, Arai Y, Sakaguchi H, Huang Y, Esaki J, Ikeda T, Tabata Y, Komeda M: New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia. Circ J 72(4): 633-640, 2008.
  58. Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K: The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats. J Clin Invest 118(3): 868-878, 2008.
  59. Takase B, Takeishi Y, Hirai T, Lee JD, Uzui H, Senda S, Miwa K, Hiraoka Y, Kinugawa T, Hosokawa R, Fujita M: Comparative effects of amlodipine monotherapy and combination therapy with betaxolol on cardiac autonomic nervous activity and health-related quality of life in patients with poorly controlled hypertension. Circ J 72(5): 764-769, 2008.
  60. Miyamoto S, Ueda M, Ikemoto M, Naruko T, Itoh A, Tamaki S, Nohara R, Terasaki F, Sasayama S, Fujita M: Increased serum levels and expression of S100A8/A9 complex in infiltrated neutrophils in atherosclerotic plaque of unstable angina. Heart 94(8): 1002-1007, 2008.
  61. Miwa K, Fujita M: Small heart syndrome in patients with chronic fatigue syndrome. Clin Cardiol 31(7): 328-333, 2008.
  62. Terasaki F, Ukimura A, Tsukada B, Fujita S, Katashima T, Otsuka K, Otsuka K, Kanzaki Y, Shimomura H, Fujita M, Tanaka T, Kitaura Y: Enhanced expression of type 1 helper T cell cytokines in the myocardium of active cardiac sarcoidosis. Circ J 72(8): 1303-1307, 2008.
  63. Fujita M, Yamazaki T, Hayashi D, Kohro T, Okada Y, Nagai R, The JCAD Study Investigators: Pleiotropic effects of statins on cardiovascular events in the Japanese Coronary Artery Disease study. Int J Cardiol 129:294-296, 2008.
  64. Morimoto T, Fujita M, Kawamura T, Sunagawa Y, Takaya T, Wada H, Shimatsu A, Kita T, Hasegawa K: Myocardial regulation of p300 and p53 by doxorubicin involves ubiquitin pathways. Circ J 72(9): 1506-1511, 2008.
  65. Miwa K, Fujita M: Gender difference in oxidative stress and its genesis by analysis of serum α-tocopherol concentrations in a Japanese population. Int J Cardiol 129:453-454, 2008.
  66. Fujita M, Morimoto T, Ono K, Terasaki F: Pleiotropic effects of sarpogrelate in cardiovascular diseases. Therapeutic Res 29(11): 1925-1931, 2008.
  67. Miwa K, Fujita M: Increased oxygen stress suggested by low serum vitamin E concentrations in patients with chronic fatigue syndrome. Int J Cardiol Aug 4. [Epub ahead of print], 2008.