2009年

14th Annual Angioplasty Summit TCT Asia Pacific 2009, 4.22-24, Seoul, Korea

1. Kimura T：Antiplatelet Therapy and Stent Thrombosis After Sirolimus-Eluting Stent Implantation.
2. Kato Y, Tamura T, Kimura T: A Case of successful repeat PCI for restenosis after Modified T-Stenting with a Sirolimus-Eluting Stent for Left Main Bifurcation Lesion.
3. Tazaki J, Toma M，Kimura T:Successful Revascularization of Intestinal Malperfusion Caused by Type B Acute Aortic Dissection.

The 5th Annual Scientific Conference at the Cardiovascular Center, NTUH Yun-Lin Branch, 8.1-3, 2009, Taiwan
Kimura T: Time Dependent Differences in the Demographics and Clinical Outcome of Stent Thrombosis of Sirolimus-eluting Stent: Final result from the RESTART (REgistry of Stent Thrombosis for review And Re-evaluaTion) registry.

ESC Congress 2009, 8.29-9.2, Barcelona, Spain

1. Kimura T: Antiplatelet therapy discontinuation and stent thrombosis of sirolimus-eluting stent: observation from the RESTART (REgistry of Stent Thrombosis for review And Re-evaluaTion).
2. Kimura T: Time dependent differences in the demographics and clinical outcome of stent thrombosis of sirolimus-eluting stent: observations from the RESTART.
3. Nagao K, Ono K, Horie T, Nishi H, Kinoshita M, Kuwabara Y, Tamaki Y, Kojima Y, Iwanaga Y, Kita T: Neural cell adhesion molecule is a cardioprotective factor upregulated by metabolic stress.
4. Miyamoto S, Inoko M, Haruna T, Oba M, Uehara K, Nakae E, Abe T, Sakaki K, Itoh H, Fukuda T, Nakashima J, Tanaka N, Ueyama K, Nohara R, Fujita M: Novel treatment with whole body periodic acceleration with a horizontal motion platform improves exercise capacity, myocardial ischemia and left ventricular function in intractable angina patients.

TCT 2009, 9.21-26, San Francisco, USA

1. Kimura T: DES Safety; Insights from Clinical Trials
2. Tazaki J，Inoue K，Toma　M，Marui A，Kimura T: Midterm Outcome of Inoue Stent Graft for the Treatment of Thoracic Aortic Aneurysm and Dissections

The 82th Scientific Sessions of American Heart Association, 11.14-18, Orlando, USA

1. Kimura T: Incidence and Outcome of Surgical Procedures After Sirolimus-eluting Stent Implantation
2. Tamura T, Tada T, Ono K, Horiuchi H, Kimura T: Aortic stenosis and acquired Type 2a von Willebrand syndrome: correlation between severity of aortic stenosis and gastrointestinal angiodysplasia (Heyde’s syndrome)
3. Shizuta S, Ando K，Nobuyoshi M，Ikeda T，Yoshino H，Hiramatsu S，Kazatani Y，Yamashiro K，Okajima K，Kajiya T，Kobayashi Y，Kato T，Fujii S，Mitsudo K，Inoue K，Ito H，Haruna Y，Nishio Y，Ozasa N，Doi T，Nishiyama K，Morimoto T， Kimura T，On behalf of the PREVENT-SCD Investigators: Prognostic Utility of T-Wave Alternans in a Real World Population of Patients with Left Ventricular Dysfunction: The PREVENT-SCD (Prospective Evaluation of Ventricular Tachyarrhythmic Events and Sudden Cardiac Death in Patients with Left Ventricular Dysfunction) Study
4. Shizuta S, Ando K，Nobuyoshi M，Ikeda T，Yoshino H，Hiramatsu S, Kazatani Y，Yamashiro K，Okajima K，Kajiya T，Kobayashi Y，Kato T，Fujii S，Mitsudo K，Inoue K，Ito H，Doi T，Morimoto T，Kimura T，On behalf of the PREVENT-SCD Investigators: Efficacy of Combined Use of T-Wave Alternans and Late Potentials in Predicting Lethal Ventricular Tachyarrhythmia among Patients with Left Ventricular Dysfunction: Insight from the PREVENT-SCD (Prospective Evaluation of Ventricular Tachyarrhythmic Events and Sudden Cardiac Death in Patients with Left Ventricular Dysfunction) Study
5. Yamamoto M, Seino Y, Okamatsu K, Inami T, Murakami D, Ohba T, Aoki S, Ibuki C, Internal Med, Chiba, Japan; Takano M, Mizuno K, Kume N: Elevation of soluble lectin-like oxidized low-density lipoprotein receptor-1 levels after plaque disruption.
6. Kato T, Niizuma S, Inuzuka Y, Kawashima T, Okuda J, Tamaki Y, Iwanaga Y, Narazaki M, Matsuda T, Soga T, Kimura T, Kita T, Shioi T: Analysis of Metabolic Remodeling in the Transition From Cardiac Hypertrophy to Failure.
7. Kishimoto C, Nimata M, Okabe T, Shioji K, Yuan Z: Olmesartan, an angiotensin II receptor type 1 antagonist, suppresses cytotoxic myocardial injury in autoimmune heart failure.
8. Kishimoto C, Yuan Z, Shioji K, Nakamura H, Yodoi J: Temocapril treatment ameliorates autoimmune myocarditis associated with enhanced cardiomyocyte thioredoxin expression.
9. Iguchi M, Akao M, Kato M, Matsumoto-Ida M, Kimura T, Kita T: Visualization Of Accumulating Reactive Oxygen Species During Myocardial Ischemia By Real-time Two-photon Imaging Of Perfused Rat Hearts.
10. Iguchi M, Akao M, Nakai J, Kato M, Takeda T, Matsumoto-Ida M, Kimura T, Kita T: Direct monitoring of mitochondrial calcium levels in cultured cardiomyocytes using a novel fluorescent indicator protein, GCaMP2-mt.
11. Ohno S, Zankov D, Ding WG, Makiyama T, Doi T, Shizuta S, Itoh H, Nishio Y, Hattori T, Matsuura H, Horie M: Novel KCNE5 Mutations Are Associated With Brugada Syndrome and Idiopathic Ventricular Fibrillation.
12. Hattori T, Makiyama T, Akao M, Ehara E, Ohno S, Nishio Y, Itoh H, Yokode M, Kimura T, Horie M: A novel gain-of-function KCNJ2 mutation associated with short QT syndrome impairs inward rectification of Kir2.1 currents.
13. Nakashima Y, Ono K, Yoshida Y, Kojima Y, Kita T, Kimura T: The identification of the NKX2-5-regulated genes using purified ES cell-derived cardiomyocytes
14. Horie T, Ono K, Iwanaga Y, Nishi H, Nagao K, Kinoshita M, Kuwabara Y, Takanabe-Mori R, Hasegawa K, Kita T, Kimura T: Acute doxorubicin cardiomyopathy is associated with miR-146a-induced inhibition of the neuregulin-ErbB4 pathway.
15. Nagao K, Ono K, Horie T, Nishi H, Kinoshita M, Kojima Y, Tamaki Y, Kuwabara Y, Iwanaga Y, Kita T, Kimura T: Neural cell adhesion molecule is a cardioprotective factor upregulated by metabolic stress.
16. Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, Takanabe-Mori R, Hasegawa K, Takemura G, Iwanaga Y, Kita T, Kimura T: MicroRNA-15b, -16, 195, and -424, which have the same seed sequence, regulate ADP-rybosylation factor-like 2 and cellular ATP levels in neonatal rat cardiomyocytes
17. Kuwabara Y, Ono K, Horie T, Nishi H, Nagao K, Watanabe S, Kojima Y, Kinoshita M, Takanabe-Mori R, Kita T, Kimura T: MicroRNA-378, which exists intronic lesion of PGC-1beta, deteriorate cardiomyocyte survival under oxidative stress.
18. Sowa N, Ono K, Horie T, Iwanaga Y, Nishi H, Nagao K, Kinoshita M, Takanabe-Mori R, Kita T, Kimura T, Hasegawa K: Let-7/miR-98 family regulates the expression fo GLUT4 by targeting Mef-2C in metabolic control of cardiomyocytes.
19. Kaichi S, Hasegawa K, Takaya T, Morimoto T, Kawamura T, Ono K, Yokoo N, Mima T, Baba S, Doi H, Yamanaka S, Nakahata T, Heike T: Inhibition of histone deacetylation markedly induces myocardial differentiation of induced pluripotent stem cells in mice.
20. Takanabe-Mori R, Ono K, Sowa N, Wada H, Takaya T, Satoh N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K: Roles of lectin-like oxidized low-density lipoprotein (LDL) receptor-1 for maintenance of normal glucose tolerance in normal and obese states.
21. Takanabe-Mori R, Ono K, Abe Y, Wada H, Takaya T, Satoh N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K: Expression of LOX-1 (OLR1) is markedly increased in the adipose tissue of high-fat diet-induced obese mice in close association with MCP-1.
22. Matsuoka T, Ohno M, Hiraoka Y, Kita T, Kimura T, Nishi E: A metalloendopeptidase nardilysin is an essential regulator for glucose and lipid metabolism.
23. Sunagawa Y, Morimoto T, Kawamura T, Takaya T, Wada H, Uemura K, Shimatsu A, Kimura T, Fujita M, Hasegawa K: Curcumin prevents the development of hypertension-induced left ventricular hypertrophy in rats.
24. Wada H, Takaya T, Morimoto T, Sunagawa Y, Fujita M, Kimura T, Fujita Y, Satoh Y, Shimatsu A, Sawamura T, Hasegawa K: Soluble lectin-like oxidized low-density lipoprotein receptor-1 is increased in sera from chronic heart failure patients with left ventricular hypertrophy.
25. Sunagawa Y, Morimoto T, Wada H, Takaya T, Kawamura T, Yanagi S, Marui A, Ikeda T, Sakata R, Shimatsu A, Kimura T, Fujita M, Hasegawa K: A natural p300-specific histone acetyltransferase inhibitor, curcumin, exerts synergistic effects with Ace inhibitor during systolic function restoration after myocardial infarction in rats.
26. Sunagawa Y, Fukuda H, Wada H, Takaya T, Marui A, Uemura K, Shimatsu A, Fujita M, Hasegawa K, Morimoto T: Novel drug-delivery system for oral curcumin that prevents systolic function deterioration after myocardial infarction in rats.

ACC.09 and i2 Summit with iScience 2009, 3.29-31, Orlando, USA
Tamura T，Mitsudo K，Kimura T，Morimoto T，Kadota K，On behalf of the j-Cypher Registry Investigators: Long-Term Clinical Outcome and the Efficacy of Final Kissing Balloon Technique After Sirolimus-Eluting Stent Implantation using Only Main Branch Stenting Technique in Coronary Bifurcation Lesions.

58th Annual Scientific Session, American College of Cardiology, 3.31, Orlando, Florida, USA
Matsumori A: Joint Session of the Japanese Circulation Society and the American College of Cardiology: Unusual Cardiomyopathies.

17th Asian Pacific Congress of Cardiology, 5.20-23, Kyoto

1. Matsumori A: Special Lecture: Global alert and response network for hepatitis C virus-derived heart diseases.
2. Matsumori A: APSC-ISCHF Joint Session: Cardiomyopathy and Heart Failure: Update.
3. Kato T, Inuzuka Y, Tamaki Y, Kawashima T, Niizuma S, Okuda J, Iwanaga Y, Kita T, Narazaki M, Matsuda T, Soga T, Shioi T: Metabolic remodeling characterizes transition from cardiac hypertrophy to failure.
4. Inuzuka Y, Okuda J, Kawashima T, Kato T, Niizuma S, Tamaki Y, Iwanaga Y, Yoshida Y, Kosugi R, Watanabe-Maeda K, Machida Y, Tsuji S, Aburatani H, Izumi T, Kita T, Shioi T: Suppression of insulin signaling improves protein homeostasis and prevents cardiac aging in mice.
5. Otsuka K, Terasaki F, Ikemoto M, Katashima T, Fujita S, Kanzaki Y, Sohmiya K, Kono T, Fujita M, Kitaura Y: Anti-inflammatory effects of S100A8/A9 on experimental autoimmune myocarditis through modulation of the proinflammatory cytokine network.
6. Takaya T, Morimoto T, Sunagawa Y, Wada H, Kawamura T, Shimatsu A, Fujita M, Fujita Y, Sawamura T, Hasegawa K: Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 in Dahl salt-sensitive rats with heart failure.
7. Wada H, Satoh N, Ono K, Morimoto T, Nakano T, Fujita M, Shimatsu A, Hasegawa K: Significance of soluble VEGF receptor-2 in cardiovascular disease.
8. Sunagawa Y, Morimoto T, Kawamura T, Takaya T, Wada H, Kuwai T, Yanagi S, Sugimoto A, Tsukashita M, Marui A, Ikeda T, Shimatsu A, Fujita M, Kita T, Hasegawa K: Combination therapy involving G-CSF and erythropoietin synergically improve LV systolic function in heart failure after MI in rat.
9. Morimoto T, Sunagawa Y, Wada H, Takaya T, Yanagi S, Sugimoto A, Tsukashita M, Marui A, Ikeda T, Fujita M, Shimatsu A, Kita T, Hasegawa K: A natural p300-specific HAT inhibitor, curcumin, possesses beneficial effects in addition to ACE inhibitor after rat myocardial infarction.
10. Miyamoto S, Inoko M, Nagai K, Haruna T, Oba M, Uehara K, Nakane E, Abe T, Sasaki K, Itoh H, Fukuda T, Nakashima J, Tanaka N, Ueyama K, Nohara R, Fujita M: Novel treatment with periodic acceleration with a horizontal motion platform improves myocardial ischemia and left ventricular function in anginal patients.
11. Katashima T, Terasaki F, Fujita M, Otsuka K, Murakami S, Kanzaki Y, Fujita S, Miyamoto S, Hiroe M, Naruko T, Ikura Y, Ueda M, Ikemoto M, Kitaura Y: Enhanced expression of S100A8/A9 complex in the myocardium of patients with acute myocardial infarction.

18th Annual Scientific Meeting of Indonesia Heart Association, 6.12-14, Jakarta
Matsumori A: IHA-APSC Joint Symposium: New biomarkers of heart failure free immunoglobulin light chains and antitroponin I antibody.

American Heart Association 49th Cardiovascular Disease Epidemiology and Prevention Annual Conference 2009, 3.11-14, Tampa, USA
Kume N, Mitsuoka H, Hayashida K, Tanaka M, Kita T: Soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) is a prognostic biomarker for acute coronary syndrome (ACS) to predict ACS recurrence or death -comparison with troponin T and C-reactive protein.
 
10th International Symposium on Mechanisms of Vasodilatation, 6.1-3, Matsushima, Miyagi, Japan
Kume N, Aramaki Y, Mitsuoka H, Toyohara M, Inagaki N, Kita T: Vascular Smooth Muscle, Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) in vascular smooth muscle cells.
 
第15回国際動脈硬化学会(International Symposium on Atherosclerosis), 6.13-18, Boston, USA
Kume N, Mitsuoka H, Hayashida K, Tanaka M, Kita T: Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a prognostic biomarker for acute coronary syndrome (ACS) to predict ACS recurrence or death.

Gordon Research Conference (Matrix Metalloproteinases), 8.30 -9.4, Les Diablerets, Switzerland

1. Nishi E: Invited presentation, Nardilysin Regulates Axonal Maturation and Myelination in the Central Nervous System.
2. Ohno M, Matsuoka T, Hiraoka Y, Kita T, Nishi E: Poster presentation, Nardilysin Regulates Axonal Maturation and Myelination in the Central and Peripheral Nervous System.

8th Pan-Pacific Connective Tissue Societies Symposium, 6.4-7, Yokosuka, Japan
Horiguchi M, Inoue T, Noda K, Nakamura T: The role of Fibulins in elastic fiber assembly of mouse aorta.

Gordon Research Conference Elastin and Elastic Fibers, 7.26-31, Biddeford, USA
Horiguchi M, Inoue T, Ohbayashi T, Hirai M, Noda K, Marmorstein LY, Nakamura T: The role of FIBULINs in elastogenesis.

アメリカ腎臓学会, 10.27-11.1, San Diego, USA

1. Tomita M, Kazama I, Asada N, Y-Higashi A, Endo S, Kita T, Fukatsu A, Economides AN, Elizabeth Robertson, Jordan A. Kreidberg, Yanagita M: BMP7 maintains nephron progenitor cells in kidney development.
2. Endo T, Okuda T, Nakamura J, Y-Higashi A, Fukatsu A, Kita T, Yanagita M: Generation of proximal tubule-specific inducible Cre mice: a powerful tool to analyze the fate of mature proximal tubule cells.
3. Y-Higashi A, Economides AN, Mortlock DP, Hogan BLM, Fukatsu A, Kita T, Yanagita M: BMP-4 plays a Role in Shaping Ureteric Bud During Kidney Development.

World Health Summit, 10.15
Yanagita M: Symposium “Improving the research condition of young scientists”

Amgen pharmaceuticals, 10.28
Yanagita M: 招待講演　Seminar “The role of USAG-1, a BMP&Wnt modulator in
kidney injury”

Regeneron pharmaceuticals, 11.3
Yanagita M:招待講演　Seminar “How kidney fails and regenerates?”

Kidney Frontier, 11.28
Yanagita M: Prenatal programming of nephron number

Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, 4.29-5.1, Washington, D.C., USA
Miyamoto S, Ueda M, Ikemoto M, Naruko T, Itoh A, Nohara R, Katashima T, Terasaki F, Fujita M: Increased serum levels and expression of S100A8/A9 complex in filtrated neutrophils in atherosclerotic plaque of unstable angina and infarcted myocardium of acute myocardial infarction.

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