2006年

The 2nd SEOUL Conference on Cardiovascular Research, 2.3-4, Seoul, Korea

1. Matsumori A. New biomarkers in cardiovascular diseases: Hepatitis C virus, cytokines, mast cell mediators, and hepatocyte growth factor.

The 55th Annual Scientific Session of the American College of Cardiology 2006, 3.11-14, Atlanta, USA

1. Doi T, Yoshida H, Ohno S, Makiyama T, Tsuji K, Nishio Y, Nishiyama K, Shizuta S, Akao M, Kimura T, Kita T, Horie M: Genetic Analysis of Hyperpolarization-activated and Cyclic Nucleotide-gated Cation Channels 4 (HCN4) in patients with Bradyarrhythmia.
2. Kimura T, Shizuta S, Taniguchi R, Ehara N, Ozasa N, Haruna Y, Toma M, Doi T, Abe M, Furukawa Y, Nakagawa Y, Takizawa A, Shimamoto M, Murakami T, Akira Yoshida, Nakajima H, Matsui S, Hanazawa M, Motofusa A, Imai Y, Teramukai S, Fukushima M, Kita T: Long-term Survival Advantage Of Coronary Artery Bypass Grafting ( Cabg ) Over Percutaneous Coronary Intervention ( Pci ) In The Real World Clinical Practice : Is It Real ?
3. Tamura T, on behalf of the j-Cypher Registry Investigators, Kazuaki Mitsudo, Kimura T, Morimoto T, Kadota K, Isshiki T, Tanaka M, Kazatani Y, Miura A, Nakashima H, Tatami R, Hazi K, Murata Y, Ohta E, Okamoto N, Yoshida H, 6-month Clinical Outcome After Implantation Of Sirolimus-eluting Stent In Bifurcation Lesions: Comparison Of Simple Versus Complex Strategy; Preliminary Results From The J-cypher Registry
4. Ozasa N, Morimoto T, Shizuta S, Furukawa Y, Taniguchi R, Toma M, Haruna Y, Abe M, Nakagawa Y, Tamura T, Ehara N, Saito N, Doi T, Takizawa A, Mitsuomi Shimamoto, Murakami T, Yoshida A, Nakajima H, Matsui S, Imai Y, Teramukai S, Fukushima M, Kita T, Kimura T： Moderate mitral regurgitation is associated with long-term prognosis in patients with coronary artery diseases undergone revascularization.
5. Haruna Y, Furukawa Y, Taniguchi R, Ehara N, Shizuta S, Mitsuoka H, Miura A, Kotoura H, Aota M, Kato H, Matsuyama E, Takahashi M, Tabata T, Miki I, Imai Y, Teramukai S, Fukushima M, Kita T, Kimura T, for the CREDO-Kyoto Investigators. Anemia Predicts Long-Term Mortality and Cardiovascular Events in Japanese Patients Undergoing Elective Revascularization: From the Coronary Revascularization Demonstrating Outcome Study in Kyoto (CREDO-kyoto).
6. Aramaki Y, Kume N, Mitsuoka H, Mukai E, Toyohara M, Inagaki N, Kita T: Lectin-like oxidized LDL receptor-1 (LOX-1) as a novel receptor for remnant-like lipoprotein particles (RLPs) in vascular smooth muscle cells.

KCS/JCS Joint Symposium: Heart Failure, 4.14, Jeju, Koreafont

1. Matsumori A. Role of inflammation in heart failure.

Angioplasty Summit 2006、4.26-28、Korea

1. Kimura T, Sizuta S，Taniguchi R, Ehara N, Ozasa N, Haruna Y, Toma M, Doi T, Abe M, Furukawa Y, Nakagawa Y, Nobuyoshi M, Okabayashi H, Mitsudo K, Komiya T, Ogawa H, Kawasuji M, Yoshida H, Takinami E, Imai Y, Teramukai S, Fukushima M, Komeda M, Kita T, for the CREDO-Kyoto Investigators. Long-term Survival Advantage of CABG over PCI in the real World Clinical Practice; Is it Real ? :Insight from the CREDO- Kyoto Registry
2. Kimura T, Morimoto T, Mitsudou K, on behalf of the j-Cypher Registry Investigators：One year Follow-up from the j-Cypher Registry
3. Nakagawa Y, Kimura T, Mitsudo K, Morimoto T, Hiasa Y, Muramatsu T, Hayashi Y, Oshima S, Baba Y, Shiode N, Yokoi Y, Sone T, Miyazaki S, Nobuyoshi M, on behalf of the j-Cypher Investigators: Six-month outcome of Sirolimus-Eluting stent with Ticlopidine antiplatelet regimen: preliminary analysis from the j-Cypher Registry. Am J of Cardiol 97 (Suppl 8B) 3D, 2006

Heart Rhythm 2006, 5.18, Boston, USA

1. Doi T, Yoshida H, Kobori A, Ohno S, Makiyama T, Tsuji K, Nishio Y, Nishiyama K, Shizuta S, Kimura T, Kita T, Horie M: KCNJ2-S369X Mutation Causes the Loss of ER Export Motif and Generates Mild Form of Andersen-Tawil Syndrome.

Polyphenols for human health; 5.25, Phuket, Tailand

1. Matsumori A. Role of Inflammation in Heart Failure and Cardiovascular Diseases.

The 9th International Heart Failure Summit: From Pathophysiology to Clinical Practice, 6.14-16, Toronto, Canada

1. Matsumori A. Inflammation mediators in heart failure.

XIV International Symposium on Atherosclerosis, 6.18-22, Rome, Italy

1. Kume N, Mitsuoka H, Hayashida K, Tanaka M, Kita T: Soluble lectin -like oxidized LDL receptor-1 (sLOX-1) is a superior serum marker for acute coronary syndrome than troponin T or H-FABP.
2. Mitsuoka H, Kume N, Hayashida K, Tanaka M, Kita T: Serum soluble SR-PSOX/CXCL16 is an independent biomarker for acute coronary syndrome.

20th IUBMB International Congress of Biochemistry and Molecular Biology, and 11th FAOBMB Congress, 6.18-23, Kyoto

1. Hirai M, Ohbayashi T, Horiguchi M, Kita T, Nakamura T: DANCE promotes elastic fiber development, an implication for future aging therapies.

The 4th European Meeting on Elastin, 7.9-12, Lyon, France

1. Nakamura T, Hirai M, Ohbayashi T, Horiguchi M: DANCE/fibulin-5 has an elastogenic activity which is inactivated by aging-associated proteolytic cleavage.
2. Nakamura T, Hirai M, Ohbayashi T, Horiguchi M: Latent TGF-b binding protein 2 is a DANCE/fibulin-5 binding protein that regulates elastic fiber assembly.

2nd World Congress 2006 International Academy of Cardiovascular Sciences, 7.14-16, Sapporo

1. Matsumori A: HCV infection in the heart.
2. Matsumori A: Role of cytokines in cardiac inflammation and heart failure.
3. Kimura T: Long-term Survival Advantage of Coronary Artery Bypass Grafting (CABG) over Percutaneous Coronary Intervention(PCI) in the Real World Clinical Practice: Is it real?
4. Shimada K, Kishimoto C, Okabe T, Murayama T, Yokode M, Kita T: Supplementation of L-NAME restores suppressive effects of exercise upon experimental murine atherosclerosis.
5. Shioi T: Role of insulin signaling pathway in cardiac hypertrophy.

World Congress of Cardiology 2006, 9.2-6, Barcelona, Spain

1. Matsumori A. Cardiomyopathies: is it all genetics?
2. Makiyama T, Akao M, Tsuji K, Doi T, Ohno S, Yoshida H, Kita T, Horie M: Na channel gene mutations are prevalent in Japanese patients with various inherited arrhythmias.
3. Tamura T, Furukawa Y, Taniguchi R, Ono K, Kita T, Kimura T. Prognostic value of serum adiponectin level in patients with congestive heart failure.
4. Kume N: Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific serum marker for acute coronary syndrome - comparisons with troponin T, H-FABP and adiponectin.

2006　European Society of Cardiology annual scientific session, 9.2- 6, Barcelona, Spain

1. Nishiyama K: Atrial Fibrillation is Significant Predictor of Sudden Cardiac Death after Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention

The 36th Annual Convention & Scientific Session, 9.16-17, Taipei, Taiwan

1. Matsumori A: Anti-inflammatory therapy for heart failure. Joint Session of APSC and TSOC.

The 11th La Jolla-Capri-Yamaguchi-Seoul Research Conference, 10.6-8, Hagi

1. Iwanaga Y: Hypertension and heart failure; Role of cardiac apelin and angiotensin II system.

Transcatheter Cardiovascular Therapeutics 2006, 10.22-27,Washington DC, USA

1. Kimura T, Mitsudo K on behalf of j-Cypher Registry, Global Perspectives on DES: Asia Pacific Insight from the interim analysis of the j-Cypher Registry
2. Imai M, Kimura T, Hosokawa H , Odashiro K, Toma M ,Ueno K, Kita T, Inoue K: Inoue Stent Graft Implantation For TAAA Involving Visceral Artery: Use of Branched Stent Graft Or Combination With Surgical Bypass : Short-To Medium-Term Results In 15 Patients.

COE国際シンポジウム「細胞内輸送?分子機構から疾患まで」11.1-2、群馬

1. Horiuchi H: Elucidation of molecular mechanism of platelet secretion.
2. Kondo H, Shirakawa R, Higashi T, Kawato M, Ikeda T, Fukuda M, Kita T, and Horiuchi H: Constitutive GDP/GTP exchange activity and secretion-dependent GTP hydrolysis activity for Rab27 in platelets.

17th Great Wall, International Congress of Cardiology ACC Symposium: Cardiology Update 2006, 11.2-5, Beijing, China

1. Matsumori A: Global network study on epidemiology & prevention of cardiovascular diseases due to infectious agents.

The 2nd China-Japan Cardiovascular Forum, 11.4, Beijing, China

1. JieXiao, Shimada M, Matsumori A: Role of aldosterone in the pathogenesis of viral myocarditis.
2. Wang L, Zhuang H, Li T, Li Y, Matsumori A: Increased concentration of NT-proBNP in people infected with hepatitis viruses.
3. Oyake N, Shimada T, Matsumori A, Murakami Y: Hepatitis C virus infection, as a risk factor of increased aortic stiffness and cardiovascular event in dialysis patients.
4. Matsumori A: Hepatocyte growth factor and free immunoglobulin light chains.
5. Morimoto T, Sunagawa Y, Fujita M,Kita T, Hasegawa K: Curcumin, a Natural p300-specific HAT Inhibitor, Prevents the Development of Heart Failure in salt-sensitive Dahl Rats.

28th World Congress of Internal Medicine, 11.10-13,Taipei, Taiwan

1. Kita T: Program Session: Hyperlipidemia and Cardiovascular Disease:Clinical in IT Era Topic: The Controversy of Triglyceride and Atherosclerosis

Joint AHA/APSC Congestive Heart Failure East vs West. Scientific Sessions 2006, American Heart Association, 11.14, Chicago, USA

1. Matsumori A. Etiology of diastolic vs systolic failure: East vs West.

The American Heart Association's Scientific Sessions 2006, 11.13-16, Chicago,USA

1. Nishio R, Matsumori A: Role of lymphangiogenetic factors in a murene model of viral myocarditis.
2. Kishimoto C, Yuan Z, Shioji K: Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis.
3. Kishimoto C, Shioji K, Nimata M, Nakamura H, Yodoi J, Tamaki S, Hashimoto T, Kawai C): Systemic oxidative stress is increased in patients with heart failure.
4. Nakagawa Y, Mitsudo K, Kimura T, Morimoto T, Shiode N, Baba Y, Nishikawa H, Honda T, Yasumoto H, Take S, Doi O, Yuda I, Nakanoue T, on behalf of j-Cypher Registry Investigators: Predictors of target lesion revascularization after implantation of Silolimus-eluting stent: from one-year clinical outcome of j-Cypher registry. Circulation 114 (Suppl. II) II-390, 2006
5. Tamura T, Mitsudo K, Kimura T, Kadota K, Abe H, Yokoi Y, Miura A, Tanaka M, Honda H, Nozaki Y, Seki S, Shimizu H, on behalf of j-CYPHER Investigators, A Prospective Registry to Evaluate an Implantation of Sirolimus-Eluting Stent in Bifurcation Lesions: Comparison of Simple versus Complex Strategy; 6-month Clinical Outcome from The j-Cypher Registry
6. Ozasa N, Taniguchi R, Abe M, Shizuta S, Haruna Y Ehara N, Furukawa Y ,Nakano A, Jong-Dae Lee, Morioka K, Tanaka　K, Takahashi ,Oda T, Minematsu S, Imai Y, Teramukai S, Fukushima M, Morimoto T, Kita T, Kimura T, on behalf of the CREDO-Kyoto Investigators:Prevalence of mitral regurgitation and their impact on prognosis in patients with coronary artery disease undergone first percutaneous coronary intervention
7. Suyama T, Taniguchi R , Haruna Y, Shizuta S, Tamura T, Toma M, Furukawa Y, Ehara N, Takashima H, Horie M, Higashita R, Asai T, Araki M , Doyama K, Fujino Y, Imai Y, Teramukai S, Fukushima M, Kita T, Kimura T, for the CREDO-Kyoto Investigators: Impact of Complete Revascularization on Long-term Outcome after Percutaneous Coronary Intervention in the Bare Metal Stent Era
8. Haruna Y, Furukawa Y, Taniguchi R, Shizuta S, Imai M, Ehara N, Konishi T, Sugita T, Nishimura K, Matoba Y, Takahashi M, Tabata T, Ishida K, Murakami T, Imai Y, Teramukai S, Fukushima M, Morimoto T, Kita T, Kimura T; on behalf of the CREDO-Kyoto Investigators: Anemia Predicts 2 Years Mortality and Cardiovascular Events in Japanese Patients Undergoing First Elective Revascularization: from the Coronary Revascularization Demonstrating Outcomes in Kyoto (CREDO- Kyoto).
9. Iwanaga Y, Kihara Y, Noguchi T, Nonogi H, Kita T, Goto Y. :Obesity should be considered into the inter-individual variability of plasma BNP levels into the diagnosis and management of heart failure.
10. Matsumoto-Ida M, Akao M, Takeda T, Kato M, Iguchi M, Kita T: Distinct cardioprotective mechanism of cyclosporin A and ischemic preconditioning against ischemia/reperfusion revealed by real-time two-photon imaging of perfused rat hearts.
11. Tsuji K, Akao M, Ishii T, Ohno S, Makiyama T, Doi T, Haruna Y, Yoshida H, Nakashima T, Kita T, Horie M: Mechanistic basis for the pathogenesis of Long QT syndrome caused by a splicing mutation in KCNQ1 gene.
12. Horie T, Ono K, Abe Y, Kawamura T, Shimatsu A, Hasegawa K, Kita T: Identification of signaling pathways that mediate the oxidative stress-induced translocation of myocardial GLUT4 using a novel lenti viral-mediated GLUT4 reporter gene.
13. Morimoto T, Kawamura T, Miyamoto S, Takaya T, Wada H, Sunagawa Y, Ikemoto M, Fujita M, Kita T, Hasegawa K: A Natural p300-specific Histone Acetyltransferase Inhibitor, Curcumin, Represses Hypertrophic Responses in Cardiac Myocytes and Prevents the Development of Hypertension-induced Heart Failure in salt-sensitive Dahl Rats
14. Morimoto T, Kawamura T, Wada H, Sunagawa Y, Fujita M , Kita T, Hasegawa K: p300-mediated Inhibition of Doxorubicin-induced Myocardial Cell Apoptosis Involves Ubiquitin-dependent p53 Degradation
15. Wada H, Ono K, Satoh N, Kameda S, Shinjo D, Abe Y, Kawamura T, Morimoto T, Nakano T, Shimatsu A, Fujita M, Hasegawa K: Soluble Flk-1 and Soluble Tie-2, Endogenous Inhibitors of Endothelial Cell-specific Angiogenic Singals, are Increased in Serum of Patients with Metabolic Syndrome.
16. Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K: Identification of GATA-4 acetylation targets by p300 during myocardial cell hypertrophy.
17. Lin X, Ishii T, Matsuoka S, Jo H, Tambara K, Yamamoto M, Fujita M, Ikeda T, Noma A, Komeda M: Control-release of MMP-1 plasmid DNA improved contractility and Na/Ca exchange of cardiomyocytes isolated from rat chronic myocardial infarction heart.
18. Bir SC, Fujita M, Hirose K, Marui A, Arai Y, Sakaguchi H, Esaki J, Huang Y, Ikeda T, Tabata Y, Komeda M: New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia.
19. Katashima T, Terasaki F, Shimomura H, Otsuka K, Tsukada B, Murakami S, Kitaura Y, Ikemoto M, Fujita M: Enhanced expression of myeloid-related protein complex (MRP 8/14) predicts the severity and risk of complications in acute myocardial infarction.
20. Wada H, Ono K, Satoh N, Kameda S, Shinjo D, Abe Y, Kawamura T, Morimoto T, Nakano T, Shimatsu A, Fujita M, Hasegawa K: Soluble Flk-1 and soluble Tie-2, endogenous inhibitors of endothelial cell-specific angiogenic signals, are increased in serum of patients with metabolic syndrome.
21. Koide Y, Seto S, Takeno M, Baba T, Kume N, Mitsuoka H, Jinnai T, Kita T, Yano K: Soluble lectin-like oxidized low-density lipoprotein receptor-1 level is a sensitive indicator of left ventricular structural derangement in dilated cardiomyopathy.

American Society for Cell Biology, 12.9-13, San Diego, USA

1. Horiuchi H: Establishment of a Novel Actin Polymerization Assay Using Cytosol and Characterization of Mammalian Formin Daam1.

Salk Institute, Juan Carlos Bellmonte Lab　セミナー、11.17,La Jolla, USA.

1. Yanagita M: Balance between BMP and BMP antagonists in the kidney diseases

Genzyme corporation 招聘講演、2.27, Framingham, USA.

1. Yanagita M: Therapeutic targets of kidney diseases. Lessons from Gas6 and USAG-1.

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