2004年

Medical Frontline Seminar, 11-7-13, New Orleans, U.S.A.

1. Kita T

14th Asian Pacific Congress of Cardiology, 1.14-17, Singapore

1. Matsumori A, Kinoshita M, Miyazaki S, Takano H, Obata J, Tsuyuguchi N, Nonogi H, Daikoku S, Mitsudo K, Matsunaga Y, Ohnisi T, Daikuhara Y, Sasayama S. Diagnosis of arterial thrombosis by circulationg hepatocyte growth factor in patients with unstable angina pectoris and other diseases.
2. Matsumori A. Hepatitis C virus infection as a cause of cardiomyopathies and myocarditis.

International Heart Failure Symposium-Hong Kong 2004 Update in Assessment and Management, 2.21-22, Hong Kong

1. Matsumori A. Clinical implications of the ARCH-J and CHARM trials.
2. Matsumori A. Heart failure: The Asian perspective - Japan.

　

Keystone Symposia, 2.28-3.4, Taos, U.S.A.

1. Higuchi H, Miyamoto T, Kinoshita M, Yamada T, Uchiyama K, Yamamoto K, Matsumori A. Role of mast cells in the pathogenesis of viral myocarditis. mast cells is physiology, host defense and disease: Beyond IgE.
2. Matsumori A. Contribution of mast cells in the development of congestive heart failure. mast cells in physiology, host defense and disease: Beyond IgE.

XVIII World Congress, International Society for Heart Research, 8.7-10, Brisbane, Australia

1. Matsumori A. Inflammation and therapeutic strategies for viral heart diseases.

8th Annual Scientific Meeting, Heart Failure Society of America, 9.12-15, Toronto, Canada

1. Higuchi H, Miyamoto T, Kinoshita M, Yamada T, Uchiyama K, Matsumori A. Role of mast cells in the pathogenesis of heart failure due to myocarditis: Mast cells as a therapeutic targets.
2. Nishio R, Matsumori A, Okazaki T, Tanaka Y, Mitsuiye T, Mizoguchi A, Hiai H, Minato N, Honjo T. The Role of autoantibodies against cardiac troponin I in autoimmune dilated cardiomyopathy.
3. Matsumori A, Chapman NM, Tracy SM, Mason JW. Hepatitis C virus infection as a cause of heart failure and myocarditis in the myocarditis treatment trial. 8th Annual Scientific Meeting, Heart Failure Society of America, September 12-15, 2004, Toronto, Canada

First Global Conference on Cardiovascular Clinical Trial and Pharmacotherapy, 10.1-3, Hong Kong

1. Yamamoto K, Shioi T, Miyamoto T, Sasayama S, Matsumori A. Prevention of viral myocarditis by histamine 1 receptor antagonism.
2. Matsumori A, Chapman NM, Tracy SM, Mason JW. Role of hepatitis C virus infection in the pathogenesis of heart failure and myocarditis in the myocarditis treatment trial.
3. Matsumori A. New treatment of myocarditis and heart failure.

The 6th International Symposium on Hypertension and related diseases, 10.17, Beijing, China

1. Matsumori A. Clinical implications of the ARCH-J and CHARM trials.

Chronic viral and inflammatory cardiomyopathy. Workshop 55, 10.27-29, Berlin, Germany

1. Matsumori A. The role of hepatitis C virus in dilated cardiomyopathy.

The 77th Scientific Sessions of the American Heart Association, 11.7-11, New Orleans, U.S.A.

1. Matsumori A, Chapman NM, Tracy SM, Mason JW. Hepatitic C virus infection as a cause of myocarditis and heart failure.
2. Tambara K, Ooba M, Hosokawa R, Premaratne G U, Kanemitsu N, Lin X, Nakajima H, Yamamoto M, Tabata Y, Fujita M, Ikeda T: Effects of skeletal myoblast transplantation, bFGF administration, and the combination on tissue blood flow and left ventricular remodeling in rat infarcted hearts: Comparison using pin-hole SPECT.
3. Takenaka H, Kihara Y, Iwanaga Y, Onozawa Y, Toyokuni S, Kita T: Novel Mechanism of Matrix Metalloproteinase Inhibitor in the Treatment of Heart Failure : Direct Inhibition of Myocardial Oxidant Stress and NF-kB Activation in Rats.
4. Kishimoto C, Kurokawa M, Ochiai H: Immunoglobulin therapy suppresses murine influenza virus myocarditis.
5. Tsuji K, Akao M, Ishii T, Ohno S, Makiyama T, Takenaka K, Doi T, Kiyohara Y, Horie M: Quantitative Analysis of Aberrant Splicing Caused by a Splice-site Mutation in KCNQ1 Gene of a Patient with Long QT Syndrome.
6. Makiyama T, Akao M, Tsuji K, Doi T, Ono S, Takenaka K, Yanagisawa F, Kobori A, Ninomiya T, Takano M, Makita N, Higashi Y, Takeyama Y, Kita T, Horie M: High-risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations.
7. Kawamura T, Ono K, Morimoto T, Yoshida Y, Abe Y, Sowa N, Hasegawa K: Hypertrophic Stimuli Induce Association of Mineralocorticoid Receptor with a Transcriptional Coactivator p300 in Cardiac Myocytes.
8. Abe Y, Ono K, Kawamura T, Morimoto T, Miyamoto S, Shimatsu A, Hasegawa K: Leptin induces elongation of cardiac myocytes through the activation of JAK2/STAT3 cascade.
9. Miyamoto S, Morimoto T, Kawamura T, Ono K, Kawase Y, Kita T, Hasegawa K: Histone Acetyltransferase Activity of p300 Is Required for the Promotion of Left Ventricular Remodeling Following Myocardial Infarction in Adult Mice in Vivo.
10. Premaratne GU, Tambara K, Lin X, Kanemitsu N, Nakajima H, Teishi Y, Ikeda T, Fujita M, Komeda M: Multiple-dose implantation is a better cell delivery method than single-bolus implantation in skeletal myoblast transplantation to infarcted hearts.
11. Tambara K, Ooba M, Hosokawa R, Premaratne GU, Kanemitsu N, Lin X, Nakajima H, Yamamoto M, Tabata Y, Fujita M, Ikeda T: Effects of skeletal myoblast transplantation, bFGF administration, and the combination on tissue blood flow and left ventricular remodeling in rat infarcted hearts: comparison using pinhole SPECT.
12. Fujita M, Sakamoto S, Tambara K, Doi K, Watanabe M, Yamanaka K, Sugimoto A, Yamazato A: Dual aldosterone production in patients with left ventricular remodeling: analysis of pericardial fluid at open heart surgery.

The Third International Congress on Cardiovascular Disease, 11.26, Taipei, Taiwan

1. Matsumori A. Role of ARB in CHF treatment.

European society of cardiology Congress 2004 ,8.29,Munich, Germany

1. Nishiyama K, Okino S, Soga S, Kimura T: rimary coronary angioplasty reduces free wall rupture and improves mortality and morbidity of acute myocardial infarction.

The 51st Annual Meeting of the Society of Nuclear Medicine. 6.19-23, Philadelphia, U.S.A.

1. Ooba M, Hosokawa R, Takenaka H, Onozawa Y, Kambara N, Hirai T,Kimura T, Nohara R, Kihara Y, Kita T: Serial changes of myocardial perfusion and metabolism during heart failure transition in Dahl rats using pin-hole SPECT sysyem.
2. Kambara N, Hosokawa R, Ooba M, Mukai T, Kanoi T, Saito K, Saji H, Nohara R: Detection of vulnerable plaques : Simulation study using 18F-FDG and a catheter-based intravascular radiation detector (IVRD).
3. Mamede M, Tadamura E, Kubo S, Toyoda H, Yamamuro M, Hosokawa R, Ooba M, Kimura T, Kita T, Saga T: Comparison of myocardial blood flow induced by adenosine triphosphate and dipyridamole in patients with coronary artery disease.

American Society of Nuclear Cardiology, 9th annual scientific Session, 9.30-10.3, New York, U.S.A.

1. Hosokawa R, Ooba, M, Kambara N, Tadamura E, Kubo S, Nohara R, Kimura T, Kita T : The relationship between myocardial flow reserve and washout of Tc-99m sestamibi in patients with chronic heart.

RSNA 2004, 11.28-12.3, Chicago, USA

1. Hosokawa R, Nohara R, Ooba M, Kambara N, Tadamura E, Kimura T, Kita T: Myocardial oxidative consumption and exercise tolerance in patients with chronic heart failure ? clinical investigation using C-11 acetate PET.

International Congress on a New Dawn in Cardiovascular Protection II, Athens, Greece, 2004, 5.

1. Kihara Y, Onozawa Y, Takenaka H, Iwanaga Y, Toyokuni S, Kita T. Telmisartan Blocks Left Ventricular Remodeling by Suppressing Oxidative Stress-Mediated Breakdown of Extracellular Matrix in Rats with Salt-Sensitive Hypertension.

Invited Lecture, Department of Molecular Pharmacology, Stanford University, Palo Alto, CA, 2004, 11.

1. Kihara Y. Chronic selenium depletion and cardiac disease: its therapeutic indication.

The 13th International Vascular Biology Meeting, 6. 1-5, Toronto, Canada

1. Kita T: Scientific Advisory Committee
2. Kume N: Oxidized LDL receptors and atherogenesis.
3. Toyohara M, Kume N, Hayashida K, Inui A, Shibata Y, Kita T: Upregulated expression of SR-PSOX in macrophages by interferon gamma.
4. Shibata Y, Kume N, Hayashida K, Inui-Hayashida A, Minami M, Mukai E, Toyohara M, Arai H, Kamei K, Murayama T, Hara S, Yokode M, Kita T: Mulberry leaf extracts inhibit TNF-alpha-induced expression of lectin-like oxidized LDL receptor-1 (LOX-1) in vascular endothelial cells.
5. Iiyma M, Kume N, Kita T: Relationship of atrophic gastritis to coronary heart disease and cerebrovascular disease.
6. Kondo H, Horiuchi H, Shirakawa R, Higashi T, Tabuchi A, Fukuda M, Kita T: 'Rab27 regulates the Ca2+-induced dense-core granule secretion in platelets'

13th annual meeting of the Korean Society of Smooth Muscle Research、7.3、Korea

1. Kume N, Kita T：招待講演　Oxidized LDL receptors in atherogenesis.

Keystone symposia 'Traffic control: RabGTPases in vesicular transport' 1. 20-25, Breckenridge, Colorado, USA.

1. Shirakawa R, Higashi T, Tabuchi A, Yoshioka A, Nishioka H, Fukuda M, Kita T, and Horiuchi H: 'Rab27 regulates the Ca2+-induced dense-core granule secretion in platelets'

Japan-UK Platelet Conference, 9. 2-3, Oxford, UK

1. Horiuchi H, Shirakawa R, Higashi T, Tabuchi A, Yoshioka A, Nishioka H, Fukuda M, and Kita T: 'Munc13-4 is a novel Rab27 effector that regulates dense-core granule secretion in platelets.
2. Higashi T, Shirakawa R, Higashi T, Tabuchi A, Yoshioka A, Nishioka H, Kita T and Horiuchi H: 'Direct demonstration of involvement of the adaptor protein ShcA in the regulation of Ca2+-induced platelet aggregation.

Korea Japan Joint Symposium on Vascular Biology, 11. 4-6, Awaji-Umebutai, Japan.

1. Higashi T, Yoshioka A, Shirakawa R, Tabuchi A, Kondo H, Nishioka H, Kita T and Horiuchi H, 'Direct demonstration of involvement of the adaptor protein ShcA in the regulation of Ca2+-induced platelet aggregation.

Special lecture, University of Ottawa Heart Institute, 6. 1, Ottawa, Canada

1. Horiuchi H: 'Investigation of molecular mechanism of platelet activation'

1st Kyoto University International Symposium on "Leading Project for Biosimulation", 2.27-28, Kyoto, Japan

1. Kobori A, Sarai N, Matsuoka S, Takano M, Noma A, Kita T, Horie M: A simulation study for risk estimation of arrhythmogenesis -Additional gene variants affect the phenotype of Long QT Syndrome-.

American College of Cardiology Annual Scientific Session 2004, 3.7-10, New Orleans, U.S.A.

1. Kobori A, Sarai N, Shimizu W, Nakamura Y, Murakami T, Makiyama T, Ohno S, Takenaka K, Ninomiya T, Fujiwara T, Matsuoka S, Takano M, Noma A, Kita T, Horie M: Additional gene variants reduce effectiveness of b blockers in the LQT1 form of long QT syndrome.
2. Miyamoto S, Ikemoto M, Ueda M, Naruko T, Itoh A, Hasegawa K, Fujita M: Increased expression of myeloid related protein in infiltrated neutrophils in coronary atherosclerotic plaques of patients with unstable angina.

Heart Rhythm 2004 Scientific Sessions, 5.19-22, San Francisco, U.S.A.

1. Makiyama T, Doi T, Ono S, Kobori A, Ninomiya T, Tsuji K, Akao M, Takano M, Shimizu W, Makita N, Horie M: Analysis of SCN5A gene mutation in Japanese patients with arrhythmia.
2. Kobori A, Washizuka T, Murakami T, Inoue T, Yamanouchi H, Aizawa Y, Kita T, Horie M: Genotypic/phenotypic characteristics in 11 Japanese patients with KCNJ2- Andersen syndrome.

The 31st International Congress on Electrocardiology, 6.27-7.1, Kyoto, Japan

1. Kobori A, Inoue T, Hosaka Y, Washizuka T, Murakami T, Yamanouchi H, Ushinohama H, Nakamura T, Ai T, Aizawa Y, Kita T, Horie M: Genotypic/phenotypic characteristics in Japanese patients with KCNJ2 -associated Andersen-Tawil syndrome.

Gordon Research Conference (Proteolytic Enzyme & the Inhibitors),7.4-9, New London, NH, USA.

1. Nishi E, Nardilysin, Metalloendopeptidase of M16 family, Induces the Ectodomain Shedding of HB-EGF.

American Society of Nephrology Renal Week, 10.27-11.1, St. Louis, USA

1. Yanagita M: USAG-1: a novel BMP antagonist abundantly expressed in the kidney.

The 5th International Conference on BMP, 9.12-16, Nagoya

1. Yanagita M: USAG-1 as a novel BMP antagonist abundantly expressed in the kidney.

The Society for Neuroscience 34th Annual Meeting, 10.23-27, San Diego, USA

1. Okuda T: NDRG1 is essential for maintenance of the myelin sheaths in peripheral nerves.

The ENMC International Workshop on Neuromuscular Diseases in Gypsies, 4.23-25, Naarden, The Netherlands

1. Okuda T: Ndrg1 knock-out mice? Clinical and molecular phenotypes.

American Collegue of Cardiology 53nd Annual Scientific Session 2004. 3. 31-4.3 New Orleans, USA

1. Miyamoto S, Ikemoto M, Ueda M, Naruko T, Itoh A, Hasegawa K, Fujita M: Increased Expression of Myeloid Related Protein in Infiltrated Neutrophils in Coronary Atherosclerotic Plaques of Patients With Unstable Angina.

1st Annual Symposium of the American Heart Association Council on Basic Cardiovascular Sciences: Stress Signals, Molecular Targets and the Genome 2004, 7. 15-16, Stevenson, USA

1. Kawamura T, Ono K, Miyamoto S, Morimoto T, Hasegawa K: The role of p300 protein in the regulation of myocardial cell hypertrophy and apoptosis in adult mice in vivo.
2. Ono K, Hirai M, Morimoto T, Kawamura T, Wada H, Kita T, Hasegawa K. FOG-2 competes with GATA-4 for a transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.
3. Ono K, Kawamura T, Sowa N, Hasegawa K. Contribution of caveolin-1a and Akt to TNF-a-induced cell death.

Copyright(C) by Department of the circulatory organs,
Kyoto University Hospital. All Rights Reserved.