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1999年

  1. Sasayama S: The RALES study: secondary endpoints. 48th Annual Scientific Session of the American College of Cardiology, Satellite Symposium "Aldosterone Antagonists: A New Hope for Heart Failure Patients". March 6, New Orleans.
  2. Sasayama S: Cytokine network and heart failure. Scientific Conference on Molecular, Cellular, and Integrated Physiological Approaches to the Failing Heart. August 18-22, Salt Lake City.
  3. Sasayama S: Implications of the RALES findings on cardiovascular morbidity. 21st Congress of the European Society of Cardiology, Symposium "RAAS Antagonism: The RALES Study and Beyond". August 30, Barcelona.
  4. Sasayama S: Cytokines in cardiac hypertrophy: mechanisms of biosynthesis and preventive therapies. Heart Failure 2000, Septemer 30-October 2, Rome.
  5. Sasayama S: Roles of cytokines in heart failure. Case Western Reserve University, Special Lecture. November 5, Cleveland.
  6. Sasayama S: Roles of cytokines in heart failure. University of Vermont, Special Lecture. November 11, Burlington.
  7. Matsumori A: Cytokines as specific targets in CHF therapy. 8th International Congress on Cardiovascular Pharmacotherapy. March 28-April 1, Amsterdam, The Netherlands.
  8. Matsumori A: Pathogenesis of myocardial injury: Roles of cytokines, mast cells and chymase. 6th CGGH Symposium "Roles of proteolysis in health and disease". May 19-21, Naruto, Tokushima.
  9. Hara M, Matsumori A, Ono K, Kido H, Hwang MW, Miyamoto T, Iwasaki A, Okada M, Nakatani K, Sasayama S: Mast cells cause cardiomyocytes and proliferation of other intramyocardiall cells in vitro. 6th CGGH Symposium "Roles of proteolysis in health and disease". May 19-21, Naruto, Tokushima.
  10. Matsumori A: Clinical aspects of cytokines in heart failure. New therapeutic approaches. Heart Failure'99. Third international meeting organized by the working group on heart failure of the European Society of Cardiology. June 5-8, Goteborg, Sweden.
  11. Matsumori A: myocarditis and cardiomyopathy: Roles of viruses and cytokine International symposium on immunology of myocardial disease. September 7-10, Wuhan, China.
  12. Matsumori A: Hepatitis C virus and cardiomyopathy. From genes to therapy in coronary heart disease and cardiomyopathy. October 8-9, Marburg, Germany.
  13. Kasuno K, Muso E, Ono T, Takeda T, Nogaki F, Shirakawa K, Fukushima H, Kobayashi I, Watanage H, Matsumori A, Sasayama S: Chronic hepatitis C virus (HCV)infection aggravates interstitial change: A clinicopathologic and quantitative morphometric study in patients with membranous nephropathy (MN) The 3rd Tsurumai Seminer on Tubulointerstitial Injury. February 13, Nagoya.
  14. Makino T, Nakamura T, Ono T, Muso E, Honda G: Suppressibe effects of perillae herba on mesangial proliferative glomerulonephritis in rats. The 10th International Congress of Oriental medicine. May 27-28, Tokyo.
  15. Ono T, Liu N, Nogaki F, Suyama K, Fukushima H, Muso E, Sasayama S: Antiproliferative effect of benidipine hydrochloride on cultured human mesangial cells. The 36th Congress of the ERA-EDTA Europian Renal Assosiation. September 5-8, Madrid, Spain.
  16. Takeda T, Muso E, Maeda M, Ono T, Higashi Y, Takeshita K, Konishi N, Kuwahara T, Sasayama S: Two-year randomized controlled trial of steroid therapy for adult patients with moderately active IgA nephropathy (IgA-N) The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  17. Suyama K, Takeda T, Yashiro M, Muso E, Sasayama S: Angiotensin Ⅱ(AⅡ)has a pivotal role in glomerular cell proliferation in rat experimental FSGS through induction of macrophage infiltration, TNF αsecretion, and protooncogene expression. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  18. Kasuno K, Muso E, Ono T, Masutani H, Nakamura H, Sasayama S, Yodoi J: Redox regulation in renal ischemia/hypoxia: expression of thioredoxin and glutaredoxin in renal ischemia/hypoxia. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  19. Kasuno K, Muso E, Ono T, Masutani H, Nakamura H, Sasayama S, Yodoi J: Redox regulation in renal ischemia/hypoxia: Roll of thioredoxin in renal ischemia/hypoxia. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  20. Kusano H, Muso E, Nogaki F, Kobayashi I, Kamata T, Ono T, Miyawaki S, Yoshida H, Sasayama S: The effects of temocapril in high IgA strain (HIGA)of ddY mice. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  21. Shirakawa K, Muso E, Ono T, Uno K, Kishida T, Yodoi J, Sasayama S: Quantification of urinary thioredoxin / Adult-T cell leukemia Derived Factor (TRX/ADF) The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  22. Ono T, Liu N, Makino T, Nakamura T, Matsuyama K, Kusano H, Muso E, Honda G, Sasayama S: Factor V expression in the mesangial fibrin production in experimental mesangioproliferative glomerulonephritis. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  23. Liu N, Ono T, Nogaki F, Suyama K, Muso E, Sasayama S: Extracellular matrix accumulation through fibrin formation via factor V expression on cultured mesangial cells. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  24. Makino T, Ono T, Nakamura T, Muso E, Honda G, Sasayama S: Suppresive effect of rosmarinec acid on mesangioproliferative glomerulonaphritis in rats. The 32nd Annual Meeting of The American Society of Nephrology. Novemver 5-8, Miami.
  25. Hosokawa R, Nohara R, Kataoka K, Hirai T, Fujibayashi Y, Okuda K, Fujita M, Konishi J, Tamaki N, Sasayama S: Myocardial oxidative metabolism is promoted by repeat ischemia: experimental validation with I-123 BMIPP. 4th International Conference of Nuclear Cardiology. April 18-21, Athens.
  26. Hirai T, Nohara R, Ogou S, Chin L, Hosokawa R, Taguchi S, Fujibayashi Y, Sasayama S: Serial evaluation of fatty acid metabolism and mitochondrial function in rat heart with myocardial ischemia using pinhole SPECT. 4th International Conference of Nuclear Cardiology. April 18-21, Athens.
  27. Tadamura E, Kudoh T, Inubushi M, Kubo S, Okada T, Magata Y, Nohara R, Matsumori A, Sasayama S, Yoshibayashi M, Yonemura T, Konishi J: Steal phenomenon in pediatric hypertrophic cardiomyopathy after dipyridamole infusion. The 46th Annual Meeting of the Society of Nuclear Medicine. June 6-10, California.
  28. Ishihara S, Imai M, Makita S, Nakae K, Matsuura Y, Hashimoto T, Nohara R: Immune function and psychological factors in patients with coronary heart disease. 20th Congress of Woman scientists Forum. July 29, Kyoto.
  29. Kanda H, Nohara R, Hasegawa K, Morimoto T, Kihara Y, Fujita M, Sasayama S: A nuclear complex of PPAR and p300 is markedly downregulated in hypertrophied left ventricular myocardium of adult rats. The 3rd Annual Scientific Meeting of the Heart Failure Society of America. September 22-25, San Francisco.
  30. Kanda H, Nohara R, Hasegawa K, Morimoto T, Fujita M, Iwanaga Y, Sasayama S: A nuclear complex of PPAR/p300 is markedly down-regulated in hypertrophied rat left ventricular myocardium with normal systolic function. The 72nd Scientific Meeting of the American Heart Association. November 7-10, Atlanta.
  31. Hosokawa R, Nohara R, Hirai T, Inada H, Kataoka K, Masuda D, Kanda H, Tadamura E, Inubushi M, Konishi J: Importance of oxidative metabolism in definition of heart failure state and prediction of cardiac events. The 72nd Scientific Meeting of the American Heart Association. November 7-10, Atlanta.
  32. Masuda D, Nohara R, Hirai T, Chen L, Inubushi M, Tadamura E, Fujita M: The new therapeutic approach with the enhanced external counterpulsation in patients with chronic stable angina: Evaluation of myocardial flow and flow reserve by N-13-Ammonia PET. The 72nd Scientific Meeting of the American Heart Association. November 7-10, Atlanta.
  33. Otani H, Takano M, Xie LH, Tsuji K, Sakurai T, Maeda R, Akao M, Murakami T, Horie M: Subcellular localization of Kir6.x proteins. The 3rd Conference on ABC Proteins and Ion Channels -From Gene to Disease -. March 12-13, Kyoto.
  34. Otani H, Yoshida H, Horie M: HERG channel dysfunction in Japanese patients with long QT syndrome. The 3rd Conference on ABC Proteins and Ion Channels -From Gene to Disease -. March 12-13, Kyoto.
  35. Sakurai T, Otani H, Murakami T, Akao M, Maeda R, Takano M, Xie LH, Tsuji K, Horie M: Expression and subcellular localization of KATP channel in the heart. The 3rd Conference on ABC Proteins and Ion Channels -From Gene to Disease -. March 12-13, Kyoto.
  36. Xie LH, Horie M, Takano M: PLC-linked receptors regulate ATP-sensitive potassium channel via the depletion of phosphatidylinositol-4,5-bisphosphate. The 3rd Conference on ABC Proteins and Ion Channels -From Gene to Disease -. March 12-13, Kyoto.
  37. Horie M, Haruna T, Kono Y, Nawada R, Kouchi I, Otani H, Murakami T, Sasayama S: Functional cross-talk between Na/K-ATPase and ATP-sensitive K channel in ischemic preconditioning. 16th ISHR Meeting (Japanese Section) December 2-3, Fukuoka.
  38. Horie M, Yoshida H: An antiarrhythmic agent with class 1b action, arpindine, inhibits human IKr but not IKs heterologously expressed in COS7 cells. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  39. Horie M, Yoshida H, Otani H, Kawashima T, Ohnishi K: Bradycardia-Induced acquired longQT syndrome caused by a de novo missense mutation in the S2-S3 innerloop of HERG. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  40. Ai T, Yoshida H, Otani H, Kubota T, Horie M: A comparizon of QT/RR slope druing exercise testing between genetically-defined LQT1 and LQT2 patients. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  41. Haruna T, Kono Y, Otani H, Takano M, Horie M: Amphipathic fatty acid metabolite, l-palmitoylcarnitine, antagonizes stimulatory action of phosphatidylinositol-4, 5, -bisphosphate on cardiac ATP-sensitive K+ channels. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  42. Kubota T, Horie M, Takano M, Yoshida H, Sasayama S: Cell swelling-induced enhancement of IKs is phosphorylation- independent process and requires KCNQ1 as a sensor of membrane stretch. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  43. Xie LH, Takano M, Horie M: Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel via depletion of phsophatidylinositol-4,5-bisphosphate (PIP2) The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  44. Inagaki K, Kihara Y, Hayashida W: Novel cardioprotective agent, JTV519, confers ischemic preconditioning-like effects through specific activation of the delta protein kinase. The 49th Annual Scientific Session, American College of Cardiology. March 9-12, New Orleans.
  45. Takeuchi Y, Kihara Y, Sasayama S: Endothelin-1 has a unique oxygen-saving effect by increasing contractile efficiency in the isolated rat heart. The 49th Annual Scientific Session, American College of Cardiology. March 9-12, New Orleans, USA.
  46. Kihara Y, Iwanaga Y, Sasayama S: Differential pathophysiological roles of angiotensin II and endothelin-1 in hypertrophic left ventricular myocardium during transition to heart failure: Studies in salt-sensitive hypertensive rats. 1st International Congress on Heart Disease- New Trends in Research, Diagnosis and Treatment. May 10-12, Washington DC.
  47. Sarai N, Kihara Y, Izumi T, Matsuoka S, Mitsuiya T, Noma A: Novel method to real-time measure individual sarcomere length in single heart cells reveled subcellular heterogeneity of the resting length and contractile properties at each sarcomere. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  48. Izumi T, Kihara Y, Yoneda T, Iwanaga Y: T-type calcium channel is induced by endothelin-1 but not by angiotensin II in adult rat myocytes in vitro and in failing left ventricular myocardium in vivo. The 72nd Scientific Sessions of American Heart Association, November 7-10, Atlanta.
  49. Inagaki K, Kihara Y, Hayashida W, Iwanaga Y, Yasaka A: Mechanical stretch induced PKCe translocation is altered in hypertrophic left ventricular myocardium of chronic pressure-overload in hypertensive rats. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  50. Iwanaga Y, Kihara Y, Yasaka A, Yoneda T, Hayashida W, Aoyama T: Regulation of osteopontin in in vivo left ventricular hypertrophy and failure: A possible relation to endogenous endothelin-1 activation. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  51. Iwanaga Y, Kihara Y, Hayashida W, Aoyama T, Sasayama S: Excess of matrix metalloproteinases over their tissue inhibitors contributes to left ventricular structural remodeling during transition from hypertrophy to heart failure in hypertensive rats. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  52. Kihara Y: Dahl salt-sensitive rat: a new model for the study of heart failure transition. Cardiology Ground Round, Division of Cardiology, Case Western Reserve University, invited lecture as a visiting professor. November 3-5, Cleveland.
  53. Kihara Y: Dahl salt-sensitive rat: a new model for the study of heart failure transition. Research Seminar, Whitaker Cardiovascular Institute, Boston University School of Medicine, invited lecture as a visiting professor. November 13, Boston.
  54. Hasegawa K, Kakita T, Morimoto T, Kaburagi S, Wada H, Sasayama S: A p300 Protein is Involved in α1-Adrenergic Agonist-Stimulated Endothelin-1 Transcription in Cardiac Myocytes as a Coactivator of GATA-4/5. Scientific Conference on Molecular, Cellular, and Integrated Physiological Approaches to the Failing Heart. August 18-22, Salt Lake City.
  55. Morimoto T, Hasegawa K, Kakita T, Kaburagi S, Wada H, Sasayama S: Phosphorylation of Cardiac GATA4 During Inducible Endothelin-1 Expression. Scientific Conference on Molecular, Cellular, and Integrated Physiological Approaches to the Failing Heart. August 18-22, Salt Lake City.
  56. Iwai-Kanai E: Calcineurin-GATA4 Pathway Is Involved in Alpha-adrenergic Agonist-mediated Protection Against Myocardial Cell Apoptosis. Third Annual Meeting of the Heart Failure Society of America. September 22-25, San Francisco.
  57. Kakita T, Morimoto T, Kaburagi S, Wada H, Hasegawa K: A p300 Protein Is Involved inα1-Adrenergic Agonist-stimulated Endothelin-1 Transcription in Cardiac Myocytes as a Coactivator of GATA-4/5. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  58. Kakita T, Iwai-Kanai E, Araki M, Fujita M, Iwakura A, Morimoto T, Hasegawa K: The Calcineurin-GATA4 Pathway is Involved in Endothelin-1-mediated Protection　Against Oxidant Stress-induced Apoptosis in Cardiac Myocytes. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  59. Kaburagi S, Kakita T, Morimoto T, Wada H, Hasegawa K: The Calcineurin-GATA4 pathway mediates β-Adrenergic Agonist-stimulated Endothelin-1 Transcription in Cardiac Myocytes. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  60. Morimoto T, Kakita T, Kanda H, Nohara R, Kaburagi S, Hasegawa K: Peroxisome Proliferator-activated Receptor-dependent Pathways Suppress Myocardial Cell Hypertrophy. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  61. Morimoto T, kakita T, Kaburagi S, Wada H, Hasegawa K: Phosphorylation of Cardiac GATA4 During Inducible Endothelin-1 Expression. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  62. Wada H, Kakita T, Morimoto T, Hasegawa K: A p300 protein is Involved in Smooth Muscle-specific Transcription as a Coactivator of GATA-6. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  63. Kaburagi S: Lisinopril Represses Hypertrophy Signaling Pathway and Endothelin-1 Synthesis in Cardiac Myocytes. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  64. Kakita T, Hasegawa K,Wada H, Morimoto T, Sasayama S: Calcineurin-GATA6 pathway controls smooth muscle-specific transcription, The 16th Annual Meeting of the Japanese Section, International Society for Heart Research (ISHR)December 1-3, Fukuoka.
  65. Shinoda E, Yui Y, Hattori R, Aoyama T, Inoue R, Takimoto Y, Tanaka M. Tissue factor pathway inhibitor-2 induces proliferation and morphological change in vascular smooth muscle cells. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  66. Kihara Y, Iwanaga Y, Hayashida W, Aoyama T, Sasayama S. Excess of matrix metalloproteinases over their tissue inhibitors contributes to left ventricular structural remodeling during transition from hypertrophy to heart failure in hypertensive rats. The 72nd Scientific Sessions of American Heart Association. November 7-10, Atlanta.
  67. Kishimoto C, Fujita M, Kinoshita M, Iwase T, Fujii B, Murashige A, Maruhashi H: Immunoglobulin therapy for myocarditis and acute dilated cardiomyopathy. The 72nd Scientific Session of the American Heart Association. November 7-10, Atlanta.
  68. Hayashida W, Kihara Y, Inagaki K, Iwanaga Y, Yasaka A, Sasayama S: Altered activation of c-Jun N-terminal kinase in the hypertrophied and failing rat left ventricular myocardium. The 48th American College of Cardiology Annual Scientific Sessions. March 9-12, New Orleans.
  69. Hayashida W, Kihara Y, Iwanaga Y, Yasaka A, Sasayama S: Long-term ACE-inhibition restored calcineurin protein expression in rat LV myocardium during transition from hypertrophy to failure. Scientific Conference on Molecular, Cellular, and Integrated Physiological Approaches to the Failing Heart. August 18-22, Salt Lake City.
  70. Hayashida W, Kihara Y, Iwanaga Y, Inagaki K, Yasaka A, Sasayama S: Cardiac troponin-T isoform change and LV contractile dysfunction in rats with heart failure: Effects of chronic endothelin receptor blockade. Scientific Conference on Molecular, Cellular, and Integrated Physiological Approaches to the Failing Heart. August 18-22, Salt Lake City.
  71. Hayashida W, Yasaka A, Inagaki K, Iwanaga Y: Stage-specific activation of motogen-activated protein kinases in subacute versus chronic hypertension in rat hearts. The 72nd Scientific Sessions of the American Heart Association. November 7-10, Atlanta.
  72. Yasaka A, Hayashida W, Kihara Y, Inagaki K, Sasayama S: Stretch-induced activation of Jak/STAT pathway is augmented in the hypertrophied rat hearts. The 16th meeting of the International Society for Heart Research, Japanese Section. December 2-3, Fukuoka.
  73. Araki M, Hasegawa K, Iwai-Kanai E, Fujita M, Sawamura T, Kaburagi S, Sasayama S: Endothelin type A receptor-dependent signaling pathways inhibit b-adrenergic agonist-induced apoptosis in cardiac myocytes. The 48th Annual Scientific Session of the American College of Cardiology. March 7-10, New Orleans.
  74. Fujita M: Angiogenic therapy: the past, the present and the future. Special lecture at Academic Medical Center, University of Amsterdam. October 28, Amsterdam.
  75. Fujita M, Lee JD, Nakae I, Miwa K: A new treatment strategy for vasospastic angina: combination therapy of short and long acting calcium channel blockers. The 4th European Meeting on Calcium Antagonists. October 27-29, Amsterdam.
  76. Motooka M, Matsuda T, Kida M, Inoue H, Hayashi K, Takahashi T, Sasayama S: Single breath-hold left ventricular volume measurement by 0.3-sec turbo fastlow-angle ot MR imaging. International Symposium on Ultrafast Magnetic Resonance Imaging in Medicine (ISUM'99) January 27-29, Kyoto.
  77. Motooka M, Yamada N, Urayama S, Takamiya M, Uyana T, Matsuda T, Sasayama S: Relationship between Circumferential Shortening and Torsion of the LeftVentricle using SPAMM-Tagged MR Imaging: Normal Control vs. Hypertrophied Heart. International Society for Magnetic Resonance in Medicine Seventh Scientific Meeting and Exhibition. May 24-28, Philadelphia.
  78. Urayama S，Matsuda T，Inoue H，et.al.: Simple Methods to Optimize a Two-phase RF Pulse Train in BURST Imaging. International Society for Magnetic Resonance in Medicine Seventh Scientific Meeting and Exhibition. May 24-28, Philadelphia.
  79. Suga M, Oshiro O, Minato K, Matsuda T, Komori M, Takahashi T, Okamoto J, Takizawa O: Measurement of Local Wavelength Using MR Elastography　with Multiple Phase Offsets. Abstracts of IEEE Medical Imaging Conference'99. October 27-30, Seattle.
  80. Iwakura A, Tabata Y, Tamura N, Ikai A, Nakamura T, Shimizu Y, Fujita M, Komeda M: A novel method to enhance sternal healing after harvesting bilateral internal thoracic arteries. The 72nd Scientific Meeting of the American Heart Association. November 7-10, Atlanta.
  81. Iwakura A, Fujita M, Hasegawa K, Araki M, Iwai-Kanai E, Sawamura T, Nohara R, Komeda M: Pericardial fluid from patients with unstable angina induces myocardial cell apoptosis via a p38 mitogen-activated protein kinase-dependent pathway. The 72nd Scientific Meeting of the American Heart Association. November 7-10,Atlanta.
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